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Found 54 with Last Name = 'murgolo' and Initial = 'n'
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  4.60nMAssay Description:Compound was evaluated for displacement of [3H]QNB from human Muscarinic m1 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM81901(AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356)
Affinity DataKi:  5.30nMAssay Description:Compound was evaluated for displacement of [3H]-QNB from human Muscarinic m2 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50347819(CHEMBL1802414 | P550)
In DepthDetails ArticlePubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50347818(CHEMBL1802413 | P518)
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM81901(AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356)
Affinity DataKi:  12nMAssay Description:Compound was evaluated for displacement of [3H]QNB from human Muscarinic m1 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50018056((AF-DX 116) 11-[2-(2-Diethylaminomethyl-piperidin-...)
Affinity DataKi:  52nMAssay Description:Compound was evaluated for displacement of [3H]-QNB from human Muscarinic m2 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289120(4-Methyl-1-[2-oxo-2-(6-oxo-5,6-dihydro-benzo[e]pyr...)
Affinity DataKi:  71nMAssay Description:Compound was evaluated for displacement of [3H]-QNB from human Muscarinic m2 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289120(4-Methyl-1-[2-oxo-2-(6-oxo-5,6-dihydro-benzo[e]pyr...)
Affinity DataKi:  82nMAssay Description:Compound was evaluated for displacement of [3H]QNB from human Muscarinic m1 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50018056((AF-DX 116) 11-[2-(2-Diethylaminomethyl-piperidin-...)
Affinity DataKi:  179nMAssay Description:Compound was evaluated for displacement of [3H]QNB from human Muscarinic m1 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM86228(P517)
Affinity DataKi:  235nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM86226(P52)
Affinity DataKi:  245nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  251nMAssay Description:Compound was evaluated for displacement of [3H]-QNB from human Muscarinic m2 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM86224(P513)
Affinity DataKi:  258nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM86227(P552)
Affinity DataKi:  607nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM86225(P51)
Affinity DataKi:  1.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Molsoft

Curated by ChEMBL
LigandPNGBDBM50232469(CHEMBL252145 | N,N-bis(tosylmethyl)hexan-1-amine)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Molsoft

Curated by ChEMBL
LigandPNGBDBM50232470(2-phenyl-N,N-bis(o-tolylthiomethyl)ethanamine | CH...)
Affinity DataKi:  7.50E+3nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Molsoft

Curated by ChEMBL
LigandPNGBDBM50232467(CHEMBL399303 | phenyl-N,N-bis(tosylmethyl)methanam...)
Affinity DataKi:  7.50E+3nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Molsoft

Curated by ChEMBL
LigandPNGBDBM50232468(6-(((3-chlorobenzyl)(methyl)amino)methyl)-N2-o-tol...)
Affinity DataKi:  7.80E+3nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Molsoft

Curated by ChEMBL
LigandPNGBDBM50232466(2-(dimethylamino)ethyl 4-(5-(4-methoxybenzylidene)...)
Affinity DataKi:  8.10E+3nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM86229(YGGFMRF-amide)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Molsoft

Curated by ChEMBL
LigandPNGBDBM50232465(4-methoxy-benzoic acid 2-diethylaminomethyl-4-(1,1...)
Affinity DataKi:  1.13E+4nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Molsoft

Curated by ChEMBL
LigandPNGBDBM50232464(CHEMBL251947 | {3-[2-(4-bromo-phenyl)-benzo[d]imid...)
Affinity DataKi:  1.19E+4nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Molsoft

Curated by ChEMBL
LigandPNGBDBM50232471(CHEMBL251948 | N-(3-(benzyl(isopropyl)amino)propyl...)
Affinity DataKi:  2.09E+4nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595797(CHEMBL5171401)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595792(CHEMBL5182418)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595793(CHEMBL5187792)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595794(CHEMBL5193119)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595796(CHEMBL5199100)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595795(CHEMBL5207556)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595797(CHEMBL5171401)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMIX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595790(CHEMBL5197877)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595793(CHEMBL5187792)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMIX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595792(CHEMBL5182418)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMIX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595791(CHEMBL5178733)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595796(CHEMBL5199100)
Affinity DataIC50:  12nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMIX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50:  20nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595794(CHEMBL5193119)
Affinity DataIC50:  24nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMIX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50:  30nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandPNGBDBM50595795(CHEMBL5207556)
Affinity DataIC50:  68nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMIX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM228835(MRL-436)
Affinity DataIC50:  2.00E+3nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM228835(MRL-436)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM228835(MRL-436)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM228835(MRL-436)
Affinity DataIC50:  4.00E+3nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM228835(MRL-436)
Affinity DataIC50:  4.00E+3nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609727(CHEMBL5279683)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human PXRMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))TBA
LigandPNGBDBM50609727(CHEMBL5279683)
Affinity DataIC50: >3.00E+4nMAssay Description:Reversible inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50609727(CHEMBL5279683)
Affinity DataIC50: >3.00E+4nMAssay Description:Reversible inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50609727(CHEMBL5279683)
Affinity DataIC50: >3.00E+4nMAssay Description:Reversible inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50609727(CHEMBL5279683)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PubMed
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