TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of cIAP1 BIR2-3 (154 to 352 residues) (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of cIAP BIR2-3 domain (unknown origin)More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of XIAP BIR3 domain (unknown origin)More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of cIAP1 BIR2-3 (154 to 352 residues) (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of cIAP1 BIR2-3 (154 to 352 residues) (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of cIAP1 BIR3 (154 to 352 residues) (unknown origin) by fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of XIAP BIR2-3 (125 to 356 residues) C202A/C213G mutant (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarizat...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition in GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Bcl-XL using fluoresceinated 18-mer Bim as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of cIAP1 BIR3 (154 to 352 residues) (unknown origin) by fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of cIAP1 BIR3 (154 to 352 residues) (unknown origin) by fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Bcl-XL using fluoresceinated 18-mer Bim as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition in GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition in GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of cIAP1 BIR3 (154 to 352 residues) (unknown origin) by fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of Bcl-XL using fluoresceinated 18-mer Bim as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition in GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Bcl-XL using fluoresceinated 18-mer Bim as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by ChEMBL
Bristol-Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of cIAP1 BIR3 (154 to 352 residues) (unknown origin) by fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Bcl-XL using fluoresceinated 18-mer Bim as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair