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Found 59 with Last Name = 'nakabayashi' and Initial = 'm'
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388528(CHEMBL2058272)
Affinity DataIC50:  0.0290nMAssay Description:Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [3H]-1alpha,25-dihydroxyvitamin D3 from recombinant human VDR LBD expressed in Escherichia coli BL21 (DE3) pLysS after 16 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50129805(CHEMBL3629552)
Affinity DataIC50:  0.210nMAssay Description:Displacement of [3H]-1alpha,25-dihydroxyvitamin D3 from recombinant human VDR LBD expressed in Escherichia coli BL21 (DE3) pLysS after 16 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388529(CHEMBL2058273)
Affinity DataIC50:  0.380nMAssay Description:Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388530(CHEMBL2058274)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015318(CHEMBL3263871)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50292705((25R)-25-Adamantyl-1alpha,25-dihydroxy-2-methylene...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at VDR expressed in COS7 cells assessed as inhibition of 1,25-Dihydroxyvitamin D3-induced response by transient transcription ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015315(CHEMBL3263870)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015317(CHEMBL3263872)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50292704((1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methy...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at VDR expressed in COS7 cells assessed as inhibition of 1,25-Dihydroxyvitamin D3-induced response by transient transcription ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015315(CHEMBL3263870)
Affinity DataEC50:  6.60nMAssay Description:Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  1.10nMAssay Description:Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015317(CHEMBL3263872)
Affinity DataEC50:  1.5nMAssay Description:Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015318(CHEMBL3263871)
Affinity DataEC50:  0.0700nMAssay Description:Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015315(CHEMBL3263870)
Affinity DataEC50:  4.40nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-RXRalpha and 4-tk-LUC assessed as heterodimerization with RXRalpha by mammal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015318(CHEMBL3263871)
Affinity DataEC50:  0.600nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-RXRalpha and 4-tk-LUC assessed as heterodimerization with RXRalpha by mammal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015317(CHEMBL3263872)
Affinity DataEC50:  2.30nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-RXRalpha and 4-tk-LUC assessed as heterodimerization with RXRalpha by mammal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  0.800nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-RXRalpha and 4-tk-LUC assessed as heterodimerization with RXRalpha by mammal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015315(CHEMBL3263870)
Affinity DataEC50:  15nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-SRC1 and 4-tk-LUC assessed as SRC1 interaction with AF2 surface of VDR by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015318(CHEMBL3263871)
Affinity DataEC50:  1.5nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-SRC1 and 4-tk-LUC assessed as SRC1 interaction with AF2 surface of VDR by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015317(CHEMBL3263872)
Affinity DataEC50:  6.5nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-SRC1 and 4-tk-LUC assessed as SRC1 interaction with AF2 surface of VDR by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  14nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-SRC1 and 4-tk-LUC assessed as SRC1 interaction with AF2 surface of VDR by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015315(CHEMBL3263870)
Affinity DataEC50:  4nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015318(CHEMBL3263871)
Affinity DataEC50:  0.400nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015317(CHEMBL3263872)
Affinity DataEC50:  3.70nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  1.80nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015315(CHEMBL3263870)
Affinity DataEC50:  4.10nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015318(CHEMBL3263871)
Affinity DataEC50:  0.5nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015317(CHEMBL3263872)
Affinity DataEC50:  2.40nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015316(CHEMBL3263873)
Affinity DataEC50:  2.80nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  0.0500nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293092(22R-Butyl-1alpha,24-dihydroxy-24,25,26-trinorvitam...)
Affinity DataEC50:  11nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293093((1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,3S)-3-(2...)
Affinity DataEC50:  1.20nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293094((1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2S,3S)-3-(2...)
Affinity DataEC50:  2nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293095(20S,22R-Butyl-1alpha,24-dihydroxy-24,25,26-trinorv...)
Affinity DataEC50:  20nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293096((1alpha,22R,24R)-22-Butyl-1,24-dihydroxyvitamin D3...)
Affinity DataEC50:  16nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293097((1alpha,22R,24S)-22-Butyl-1,24-dihydroxyvitamin D3...)
Affinity DataEC50:  3.40nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293098((1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,2S,4R)-2...)
Affinity DataEC50:  20nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293099((1alpha,22S,24S)-22-Butyl-1,24-dihydroxyvitamin D3...)
Affinity DataEC50:  3.80nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50292704((1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methy...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at VDR assessed as receptor transactivation by transient transcription assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50292705((25R)-25-Adamantyl-1alpha,25-dihydroxy-2-methylene...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at VDR assessed as receptor transactivation by transient transcription assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50292706((1R,3R,7E,17beta)-17-{(1R,2E,4R)-4-hydroxy-1-methy...)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at VDR assessed as receptor transactivation by transient transcription assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Mus musculus)
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50244164((20S)-1-alpha-25-Dihydroxy-2-alpha-(2-hydroxyethox...)
Affinity DataEC50:  0.0270nMAssay Description:Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Mus musculus)
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50244268((20S)-1-alpha-2-alpha-25-Trihydroxy-2beta-methyl-1...)
Affinity DataEC50:  0.0170nMAssay Description:Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Mus musculus)
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50244240((20S)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-eth...)
Affinity DataEC50:  0.0850nMAssay Description:Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Mus musculus)
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50412385(CHEMBL2021488)
Affinity DataEC50:  0.0900nMAssay Description:Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Mus musculus)
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50244269((20R)-1-alpha-2-alpha-25-Trihydroxy-2-beta-methyl-...)
Affinity DataEC50:  4.5nMAssay Description:Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Mus musculus)
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50244268((20S)-1-alpha-2-alpha-25-Trihydroxy-2beta-methyl-1...)
Affinity DataEC50:  1.90nMAssay Description:Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Mus musculus)
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM50244165((1R,2S,3R,5Z,7E)-17-{(1R)-1-[(2-ethyl-2-hydroxybut...)
Affinity DataEC50:  0.115nMAssay Description:Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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