TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University Of Tokushima
Curated by ChEMBL
The University Of Tokushima
Curated by ChEMBL
Affinity DataKi: 5.32E+4nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University Of Tokushima
Curated by ChEMBL
The University Of Tokushima
Curated by ChEMBL
Affinity DataKi: 7.63E+4nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University Of Tokushima
Curated by ChEMBL
The University Of Tokushima
Curated by ChEMBL
Affinity DataKi: 8.71E+4nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University Of Tokushima
Curated by ChEMBL
The University Of Tokushima
Curated by ChEMBL
Affinity DataKi: 1.97E+5nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University Of Tokushima
Curated by ChEMBL
The University Of Tokushima
Curated by ChEMBL
Affinity DataKi: 3.67E+5nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nM EC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nM EC50: 1.30nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nM EC50: 5.30nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Binding affinity of the compound in CHO cells stably expressing cloned human Opioid receptor like 1 by displacing radioligand [125I]-Tyr14-nociceptinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nM EC50: 0.720nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of [125I]SDF1 binding to CXCR4 transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of [125I]-SDF-1 binding to C-X-C chemokine receptor type 4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of [125I]SDF1 binding to CXCR4 transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of [125I]-SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of [125I]-SDF-1 binding to C-X-C chemokine receptor type 4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of [125I]Tyr14-nociceptin binding to human Opioid receptor like 1 (opioid receptor like 1) in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nM EC50: 7.5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Binding affinity of the compound in CHO cells stably expressing cloned human Opioid receptor like 1 by displacing radioligand [125I]-Tyr14-nociceptinMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of [125I]-Tyr14-nociceptin binding to human Opioid receptor like 1 (opioid receptor like 1) in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of [125I]-Tyr14-nociceptin binding to human Opioid receptor like 1 (opioid receptor like 1) in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of [125I]SDF1 binding to CXCR4 transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of [125I]-SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90nM EC50: 38nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Inhibition of [125I]-SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of [125I]-SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of [125I]SDF1 binding to CXCR4 transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of [125I]SDF1 binding to CXCR4 transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding affinity in CHO cells stably expressing cloned human Opioid receptor kappa 1 by displacing radioligand [3H]U-69593More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human ORL1 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human ORL1 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of [125I]-SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of [125I]-SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonistic activity of the compound measured by GTPgammaS binding against Opioid receptor like 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonistic activity of the compound measured by GTPgammaS binding against Opioid receptor like 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of [125I]SDF1 binding to CXCR4 transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of [125I]SDF1 binding to CXCR4 transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of [125I]-SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
Affinity DataIC50: 27nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human ORL1 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair