Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0398nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 501nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 794nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as reduction in channel tail current by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as reduction in channel tail current by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oslo
Curated by ChEMBL
University Of Oslo
Curated by ChEMBL
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as reduction in channel tail current by patch clamp methodMore data for this Ligand-Target Pair