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Found 39 with Last Name = 'o''malley' and Initial = 'pj'
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001265(3-(4-Amino-phenyl)-5,7-dichloro-4-hydroxy-1H-quino...)
Affinity DataKi:  18nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001266(5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...)
Affinity DataKi:  40nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001266(5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001266(5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...)
Affinity DataKi:  40nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004952(3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...)
Affinity DataKi:  140nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM22778(6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione | 6...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001264(5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one...)
Affinity DataKi:  300nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50129080(3-Carboxymethyl-4,6-dichloro-1H-indole-2-carboxyli...)
Affinity DataKi:  340nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002707(7,8-Dichloro-5H-[1,2,4]triazolo[4,3-a]quinoxalin-4...)
Affinity DataKi:  630nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280807(3-Carboxymethyl-5,7-dichloro-4-oxo-1,4-dihydro-qui...)
Affinity DataKi:  650nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001268(5,7-Dichloro-4-hydroxy-3-(4-nitro-phenyl)-1H-quino...)
Affinity DataKi:  860nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004960(4,6-Dichloro-1H-indole-2-carboxylic acid | CHEMBL3...)
Affinity DataKi:  980nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002696(7,8-Dichloro-5H-imidazo[1,2-a]quinoxalin-4-one | C...)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002700(1-Butyl-7,8-dichloro-5H-[1,2,4]triazolo[4,3-a]quin...)
Affinity DataKi:  1.48E+3nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002710(7,9-Dichloro-5H-[1,2,4]triazolo[4,3-a]quinoxalin-4...)
Affinity DataKi:  2.85E+3nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002701(7,8-Dichloro-1-propyl-5H-[1,2,4]triazolo[4,3-a]qui...)
Affinity DataKi:  3.92E+3nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001260(3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...)
Affinity DataKi:  4.50E+3nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002711(7,8-Dichloro-1-ethyl-5H-[1,2,4]triazolo[4,3-a]quin...)
Affinity DataKi:  4.58E+3nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50009092(3-Carboxymethyl-1H-indole-2-carboxylic acid | CHEM...)
Affinity DataKi:  5.24E+3nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81975(4-hydroxyquinoline-2-carboxylic acid | CAS_492-27-...)
Affinity DataKi:  5.40E+3nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81975(4-hydroxyquinoline-2-carboxylic acid | CAS_492-27-...)
Affinity DataKi:  5.40E+3nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280805(3-(2-Carboxy-ethyl)-5,7-dichloro-4-oxo-1,4-dihydro...)
Affinity DataKi:  7.04E+3nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002704(7-Nitro-5H-[1,2,4]triazolo[4,3-a]quinoxalin-4-one ...)
Affinity DataKi:  7.35E+3nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002712(8-Nitro-5H-1,2,3,5,9b-pentaaza-cyclopenta[a]naphth...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002695(7,8-Dichloro-5H-1,2,3,5,9b-pentaaza-cyclopenta[a]n...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002708(7-Nitro-5H-1,2,3,5,9b-pentaaza-cyclopenta[a]naphth...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002709(8,9-Dichloro-6H-pyrazolo[1,5-c]quinazolin-5-one | ...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002705(8-Chloro-6H-pyrazolo[1,5-c]quinazolin-5-one | CHEM...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002703(7,8-Dichloro-1-methyl-5H-[1,2,4]triazolo[4,3-a]qui...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002702(7,8-Dichloro-1-trifluoromethyl-5H-[1,2,4]triazolo[...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002699(7,8-Difluoro-5H-[1,2,4]triazolo[4,3-a]quinoxalin-4...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002706(7,8-Dichloro-1-phenyl-5H-[1,2,4]triazolo[4,3-a]qui...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50280806(3-Carboxymethyl-4-oxo-1,4-dihydro-quinoline-2-carb...)
Affinity DataKi:  1.48E+4nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50009085(3-Carboxymethyl-quinoline-2-carboxylic acid | CHEM...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001265(3-(4-Amino-phenyl)-5,7-dichloro-4-hydroxy-1H-quino...)
Affinity DataIC50:  210nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001264(5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one...)
Affinity DataIC50:  550nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001266(5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...)
Affinity DataIC50:  860nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001260(3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...)
Affinity DataIC50:  7.29E+3nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81975(4-hydroxyquinoline-2-carboxylic acid | CAS_492-27-...)
Affinity DataIC50:  4.02E+4nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed