Affinity DataIC50: 0.631nMAssay Description:Inhibition of MB064 probe binding to DAGLalpha in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Inhibition of full length recombinant human DAGLalpha expressed in HEK293T cell membranes using PNP butyrate as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of MB064 probe binding to DAGLalpha in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of MB064 probe binding to DAGLalpha in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of carbonic anhydrase 2 assessed as inhibition of carbon dioxide hydrationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of carbonic anhydrase 2 assessed as inhibition of carbon dioxide hydrationMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length recombinant human DAGLalpha expressed in HEK293T cell membranes using PNP butyrate as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length recombinant human DAGLalpha expressed in HEK293T cell membranes using PNP butyrate as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of MB064 probe binding to DAGLalpha in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
TargetLysophosphatidylserine lipase ABHD12(Mus musculus)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of JJH350 binding to ABHD12 in mouse brain membrane proteome incubated for 20 mins by CuAAC fluorescence dependent gel-based competitive A...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of HT-01 probe binding to recombinant mouse DAGLbeta expressed in HEK293T cell membrane proteomes preincubated for 30 mins followed by HT-...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of carbonic anhydrase 2 assessed as inhibition of carbon dioxide hydrationMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of carbonic anhydrase 2 assessed as inhibition of carbon dioxide hydrationMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
TargetLysophosphatidylserine lipase ABHD12(Mus musculus)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of JJH350 binding to ABHD12 in mouse brain membrane proteome incubated for 20 mins by CuAAC fluorescence dependent gel-based competitive A...More data for this Ligand-Target Pair
TargetLysophosphatidylserine lipase ABHD12(Mus musculus)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of JJH350 binding to ABHD12 in mouse brain membrane proteome incubated for 20 mins by CuAAC fluorescence dependent gel-based competitive A...More data for this Ligand-Target Pair
TargetLysophosphatidylserine lipase ABHD12(Mus musculus)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of JJH350 binding to ABHD12 in mouse brain membrane proteome incubated for 20 mins by CuAAC fluorescence dependent gel-based competitive A...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of HT-01 probe binding to recombinant mouse DAGLbeta expressed in HEK293T cell membrane proteomes preincubated for 30 mins followed by HT-...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of MB064 probe binding to ABHD6 in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of MB064 probe binding to ABHD6 in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured after ...More data for this Ligand-Target Pair