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Found 67 with Last Name = 'okabe' and Initial = 'm'
TargetSolute carrier organic anion transporter family member 1A4(Rattus norvegicus)
Tohoku University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Affinity DataKi:  1.80E+3nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327443(N-{3-[(1R,5S)-6-ethyl-3-azabicyclo[3.1.0]hexan-6-y...)
Affinity DataIC50:  1.30nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327436(N-(3-{(1R,5S,6r)-3-[3-(1-ethoxy-4,4-difluorocycloh...)
Affinity DataIC50:  1.30nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327428( N-(3-{(1R,5S,6r)-3-[3-(4,4-difluoro-1-methoxycycl...)
Affinity DataIC50:  1.30nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327429(N-(3-{(1R,5S,6r)-3-[3-(4,4-difluoropiperidin-1-yl)...)
Affinity DataIC50:  1.40nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327423( N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-hydroxy-2,3-dihydr...)
Affinity DataIC50:  1.5nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327426(N-(3-{(1R,5S,6r)-3-[3-(4,4-difluorocyclohexyl)prop...)
Affinity DataIC50:  1.5nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327427(N-(3-{(1R,5S,6r)-3-[3-(4,4-difluorocyclohexyl)prop...)
Affinity DataIC50:  1.60nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327437(N-(3-{(1R,5S,6r)-3-[3-(4,4-difluoropiperidin-1-yl)...)
Affinity DataIC50:  1.70nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327424(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-hydroxy-2,3-dihydro...)
Affinity DataIC50:  2nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327431(N-(3-{(1R,5S,6r)-3-[3-(3,3-difluoropyrrolidin-1-yl...)
Affinity DataIC50:  2.5nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327433(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-methoxy-2,3-dihydro...)
Affinity DataIC50:  2.80nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327430(N-(3-{(1R,5S,6r)-3-[3-(3,3-difluoropyrrolidin-1-yl...)
Affinity DataIC50:  2.90nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327438(N-(3-{(1R,5S,6r)-3-[3-(3,3-difluoropiperidin-1-yl)...)
Affinity DataIC50:  3.10nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327432(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-hydroxy-2,3-dihydro...)
Affinity DataIC50:  3.20nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327425(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-methoxy-2,3-dihydro...)
Affinity DataIC50:  3.60nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327442(N-(3-{(1R,5S,6r)-3-[(5,6-difluoro-2-hydroxy-2,3-di...)
Affinity DataIC50:  4.10nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327435(N-(3-{(1R,5S,6r)-3-[(2-ethoxy-2,3-dihydro-1H-inden...)
Affinity DataIC50:  4.10nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327441(N-(3-{(1R,5S,6r)-3-[(2-hydroxy-2,3-dihydro-1H-inde...)
Affinity DataIC50:  4.5nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327439(N-(3-{(1R,5S,6r)-3-[(2-hydroxy-2,3-dihydro-1H-inde...)
Affinity DataIC50:  5.40nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327434(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-methoxy-2,3-dihydro...)
Affinity DataIC50:  12nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327440(N-(3-{(1R,5S,6r)-3-[(2-methoxy-2,3-dihydro-1H-inde...)
Affinity DataIC50:  16nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier organic anion transporter family member 2B1(Rattus norvegicus)
Tohoku University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50101853((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...)
Affinity DataIC50:  36nMAssay Description:TP_TRANSPORTER: inhibition of PGD2 uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 2B1(Rattus norvegicus)
Tohoku University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataIC50:  287nMAssay Description:TP_TRANSPORTER: inhibition of PGD2 uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387889(CHEMBL2058666)
Affinity DataEC50:  159nMAssay Description:Agonist activity at mouse GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387890(CHEMBL2058388)
Affinity DataEC50:  2.61E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387891(CHEMBL2058389)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387892(CHEMBL2058390)
Affinity DataEC50:  145nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387893(CHEMBL2058391)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387894(CHEMBL2058394)
Affinity DataEC50:  736nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387895(CHEMBL2058395)
Affinity DataEC50:  254nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387896(CHEMBL2058396)
Affinity DataEC50:  511nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387897(CHEMBL2058397)
Affinity DataEC50:  268nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387898(CHEMBL2058399)
Affinity DataEC50:  770nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387899(CHEMBL2058400)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387902(CHEMBL2058403)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387903(CHEMBL2058404)
Affinity DataEC50:  88nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387904(CHEMBL2058405)
Affinity DataEC50:  272nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387905(CHEMBL2058406)
Affinity DataEC50:  734nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387889(CHEMBL2058666)
Affinity DataEC50:  117nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387906(CHEMBL2058667)
Affinity DataEC50:  115nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387907(CHEMBL2058668)
Affinity DataEC50:  149nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387908(CHEMBL2058669)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387909(CHEMBL2058670)
Affinity DataEC50:  161nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387910(CHEMBL2058671)
Affinity DataEC50:  704nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387911(CHEMBL2058672)
Affinity DataEC50:  121nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387912(CHEMBL2058673)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387913(CHEMBL2058674)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387893(CHEMBL2058391)
Affinity DataEC50:  224nMAssay Description:Agonist activity at mouse GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50387895(CHEMBL2058395)
Affinity DataEC50:  266nMAssay Description:Agonist activity at mouse GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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