Compile Data Set for Download or QSAR
maximum 50k data
Found 637 with Last Name = 'okasinski' and Initial = 'gf'
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107174(1-{3-[4-(2-Methoxy-phenylsulfanyl)-2,3-bis-trifluo...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(2-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107168(1-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(0.03-0.5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105186(4-(4-Trifluoromethyl-phenoxy)-thieno[2,3-c]pyridin...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105151(4-(4-Vinyl-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  1nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105186(4-(4-Trifluoromethyl-phenoxy)-thieno[2,3-c]pyridin...)
Affinity DataIC50:  1nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105227(4-[4-(Tetrahydro-pyran-2-yloxymethyl)-phenoxy]-thi...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105227(4-[4-(Tetrahydro-pyran-2-yloxymethyl)-phenoxy]-thi...)
Affinity DataIC50:  2nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107166(1-{3-[3-Chloro-4-(2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50:  2nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105151(4-(4-Vinyl-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  2nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105215(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  2nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105201(4-(4-Imidazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105155(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105215(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  3nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107168(1-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(3-6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105155(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107176(1-{3-[2,3-Dichloro-4-(1-methyl-1H-indol-5-ylsulfan...)
Affinity DataIC50:  4nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (1-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107173(1-{3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-2-trif...)
Affinity DataIC50:  4nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Selectin E expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Selectin E in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105196(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  4nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105178(4-(4-Iodo-phenoxy)-thieno[2,3-c]pyridine-2-carboxy...)
Affinity DataIC50:  4nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105195(4-(4-Pyrazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-2...)
Affinity DataIC50:  4nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105195(4-(4-Pyrazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-2...)
Affinity DataIC50:  4nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107169(1-{3-[4-(1-Methyl-1H-indol-5-ylsulfanyl)-2,3-bis-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(5-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105183(4-(4-Furan-2-yl-phenoxy)-thieno[2,3-c]pyridine-2-c...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098480(4-(4-Bromo-phenylsulfanyl)-thieno[2,3-c]pyridine-2...)
Affinity DataIC50:  5nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107162(3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-2-trifluo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (3-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107166(1-{3-[3-Chloro-4-(2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (4-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107169(1-{3-[4-(1-Methyl-1H-indol-5-ylsulfanyl)-2,3-bis-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(3-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105196(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105205(4-(4-Imidazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105195(4-(4-Pyrazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-2...)
Affinity DataIC50:  5nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105172(4-[4-(2-Methoxy-ethoxymethyl)-phenoxy]-thieno[2,3-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced Selectin E in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105183(4-(4-Furan-2-yl-phenoxy)-thieno[2,3-c]pyridine-2-c...)
Affinity DataIC50:  5nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory potency compared to PMA induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105164(4-(4-Thiophen-2-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105180(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107174(1-{3-[4-(2-Methoxy-phenylsulfanyl)-2,3-bis-trifluo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(4-6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107164(3-[2,3-Dichloro-4-(2-methoxy-phenylsulfanyl)-pheny...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105181(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107176(1-{3-[2,3-Dichloro-4-(1-methyl-1H-indol-5-ylsulfan...)
Affinity DataIC50:  6nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107181(1-{3-[2,3-Dichloro-4-(2-isopropyl-phenylsulfanyl)-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (3-18)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 637 total ) | Next | Last >>
Jump to: