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Found 159 with Last Name = 'omar' and Initial = 'ha'
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of CYP2D6 (unknown origin) using EOMCC as a substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  37nMAssay Description:Inhibition of Flt4 (unknown origin) in presence of [gamma33]-ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  39nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50117930((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...)
Affinity DataIC50:  43nMAssay Description:Inhibition of hERG measured by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataIC50:  55nMAssay Description:Inhibition of CYP3A4 (unknown origin) using BOMCC as a substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant full-length GST-tagged human B-RAF V600E mutant (417 to 766 residues) expressed in Baculovirus infected Sf9 cells using N-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  80nMAssay Description:Inhibition of His-6 tagged recombinant EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in Baculovirus infected Sf9 cells by...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM16018(14,15-diazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexa...)
Affinity DataIC50:  91nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  92nMAssay Description:Inhibition of KDR (unknown origin) in presence of [gamma33]-ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50562672(CHEMBL4797840)
Affinity DataIC50:  96nMAssay Description:Inhibition of Flt4 (unknown origin) in presence of [gamma33]-ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50:  97nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50:  98nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592449(CHEMBL5201911)
Affinity DataIC50:  99nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592449(CHEMBL5201911)
Affinity DataIC50:  100nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261639(CHEMBL4076689)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261633(CHEMBL4079032)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261638(CHEMBL4073779)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261640(CHEMBL4096865)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261634(CHEMBL4097045)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50562672(CHEMBL4797840)
Affinity DataIC50:  173nMAssay Description:Inhibition of KDR (unknown origin) in presence of [gamma33]-ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261643(CHEMBL4071061)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592447(CHEMBL5196004)
Affinity DataIC50:  190nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592447(CHEMBL5196004)
Affinity DataIC50:  191nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50504119(CHEMBL4540180)
Affinity DataIC50:  230nMAssay Description:Inhibition of human NPP3 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50504116(CHEMBL4473374)
Affinity DataIC50:  290nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50207432(CHEMBL3909479)
Affinity DataIC50:  320nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in oxidation of TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in oxidation of TMPD using arachidonic acid as substrate preincubated for 5 mins followed...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261644(CHEMBL4072244)
Affinity DataIC50:  360nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592470(CHEMBL5189795 | US20240002365, Compound CTx-029488...)
Affinity DataIC50:  370nMAssay Description:Inhibition of JNK3 in human HEK293 cells transfected with JNK3-NanoLuc fusion vector measured after 1 hr by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50207431(CHEMBL3892572)
Affinity DataIC50:  420nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in oxidation of TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50504120(CHEMBL4589775)
Affinity DataIC50:  420nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  427nMAssay Description:Inhibition of PDGFRalpha (unknown origin) in presence of [gamma33]-ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50504118(CHEMBL4456605)
Affinity DataIC50:  450nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261636(CHEMBL4065185)
Affinity DataIC50:  450nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592454(CHEMBL5205920)
Affinity DataIC50:  474nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592454(CHEMBL5205920)
Affinity DataIC50:  479nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50504124(CHEMBL4561757)
Affinity DataIC50:  490nMAssay Description:Inhibition of human NPP3 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  490nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261642(CHEMBL4073566)
Affinity DataIC50:  520nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592448(CHEMBL5183673)
Affinity DataIC50:  525nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592448(CHEMBL5183673)
Affinity DataIC50:  526nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50207435(CHEMBL3960755)
Affinity DataIC50:  540nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in oxidation of TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261637(CHEMBL4092847)
Affinity DataIC50:  560nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592455(CHEMBL5179126)
Affinity DataIC50:  614nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592455(CHEMBL5179126)
Affinity DataIC50:  617nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50207430(CHEMBL3924357)
Affinity DataIC50:  670nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in oxidation of TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50261641(CHEMBL4074351)
Affinity DataIC50:  680nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation by measuring PGF2alpha by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50504116(CHEMBL4473374)
Affinity DataIC50:  710nMAssay Description:Inhibition of human NPP3 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  710nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in oxidation of TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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