Compile Data Set for Download or QSAR
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Found 85 with Last Name = 'osman' and Initial = 'w'
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199186(N-(3,4-Dimethoxybenzyl)-1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199186(N-(3,4-Dimethoxybenzyl)-1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50:  20nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  40nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  40nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's metho...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's m...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199199(N-(Pyridin-2-ylmethyl)-1,2,3,4-tetrahydroacridin-9...)
Affinity DataIC50:  70nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199184(N-(3-Methoxybenzyl)-1,2,3,4-tetrahydroacridin-9-am...)
Affinity DataIC50:  80nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199196(N-(3,4-Dimethoxyphenethyl)-1,2,3,4-tetrahydroacrid...)
Affinity DataIC50:  80nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199201(6-Chloro-N-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  90nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199201(6-Chloro-N-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  90nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199183(N-(2-Methoxybenzyl)-1,2,3,4-tetrahydroacridin-9-am...)
Affinity DataIC50:  90nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  160nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's metho...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in insect cells using DBOMF as substrate pretreated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199202(6-Chloro-N-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  200nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199200(N-(Pyridin-3-ylmethyl)-1,2,3,4-tetrahydroacridin-9...)
Affinity DataIC50:  200nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199185(N-(4-Methoxybenzyl)-1,2,3,4-tetrahydroacridin-9-am...)
Affinity DataIC50:  200nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199201(6-Chloro-N-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  240nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)
Affinity DataIC50:  340nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranesMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199182(N-benzyl-1,2,3,4-tetrahydroacridin-9-amine (8a))
Affinity DataIC50:  400nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199197(6-Chloro-N-(3,4-dimethoxyphenethyl)-1,2,3,4-tetrah...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199188(6-Chloro-N-(3-methoxybenzyl)-1,2,3,4-tetrahydroacr...)
Affinity DataIC50:  600nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199197(6-Chloro-N-(3,4-dimethoxyphenethyl)-1,2,3,4-tetrah...)
Affinity DataIC50:  600nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199189(6-Chloro-N-(4-methoxybenzyl)-1,2,3,4-tetrahydroacr...)
Affinity DataIC50:  700nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199190(6-Chloro-N-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199190(6-Chloro-N-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  800nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199195(7-Chloro-N-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  1.30E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199190(6-Chloro-N-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199190(6-Chloro-N-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  1.40E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199201(6-Chloro-N-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  1.60E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199201(6-Chloro-N-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM8997(N-Benzyl-6-chloro-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  1.70E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199193(7-Chloro-N-(3-methoxybenzyl)-1,2,3,4-tetrahydroacr...)
Affinity DataIC50:  1.90E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199197(6-Chloro-N-(3,4-dimethoxyphenethyl)-1,2,3,4-tetrah...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199197(6-Chloro-N-(3,4-dimethoxyphenethyl)-1,2,3,4-tetrah...)
Affinity DataIC50:  1.90E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199186(N-(3,4-Dimethoxybenzyl)-1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50:  2.20E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199186(N-(3,4-Dimethoxybenzyl)-1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199185(N-(4-Methoxybenzyl)-1,2,3,4-tetrahydroacridin-9-am...)
Affinity DataIC50:  2.20E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199187(6-Chloro-N-(2-methoxybenzyl)-1,2,3,4-tetrahydroacr...)
Affinity DataIC50:  2.40E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199191(N-Benzyl-7-chloro-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  2.60E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  2.60E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199187(6-Chloro-N-(2-methoxybenzyl)-1,2,3,4-tetrahydroacr...)
Affinity DataIC50:  3.00E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199198(7-Chloro-N-(3,4-dimethoxyphenethyl)-1,2,3,4-tetrah...)
Affinity DataIC50:  3.10E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199184(N-(3-Methoxybenzyl)-1,2,3,4-tetrahydroacridin-9-am...)
Affinity DataIC50:  3.30E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Waterloo

LigandPNGBDBM199194(7-Chloro-N-(4-methoxybenzyl)-1,2,3,4-tetrahydroacr...)
Affinity DataIC50:  3.40E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  3.60E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199186(N-(3,4-Dimethoxybenzyl)-1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50:  3.70E+3nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme in Hog plasmaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM8997(N-Benzyl-6-chloro-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  4.00E+3nMpH: 8.0 T: 2°CAssay Description:Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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