Compile Data Set for Download or QSAR
maximum 50k data
Found 47 with Last Name = 'otal' and Initial = 'r'
TargetCyclin-dependent kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50611418(CHEMBL5271655)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50611421(CHEMBL5276637)
Affinity DataIC50:  70nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50611421(CHEMBL5276637)
Affinity DataIC50:  160nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM153386(2-(4,5-Dibromo-1H-pyrrole-2-carbonyl)-N-(4-chlorop...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of MMP-2 (unknown origin) using succinylated gelatin as substrate incubated for 80 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611424(CHEMBL5274960)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611423(CHEMBL5269966)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611425(CHEMBL5280295)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611426(CHEMBL5267416)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611427(CHEMBL5279459)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611428(CHEMBL5287845)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611422(CHEMBL5289025)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))TBA
LigandPNGBDBM50509086(CHEMBL4539558)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVIP peptides(Homo sapiens (Human))TBA
LigandPNGBDBM50611420(CHEMBL5285378)
Affinity DataIC50:  1.92E+4nMAssay Description:Displacement of [125I]-VIP from Vasoactive intestinal peptide (unknown origin) incubated for 120 mins by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetVIP peptides(Homo sapiens (Human))TBA
LigandPNGBDBM50611419(CHEBI:80954 | SCEPTRIN | Sceptrin)
Affinity DataIC50:  1.98E+4nMAssay Description:Displacement of [125I]-VIP from Vasoactive intestinal peptide (unknown origin) incubated for 120 mins by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))TBA
LigandPNGBDBM50509084(CHEMBL4531006)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50509086(CHEMBL4539558)
Affinity DataIC50:  2.96E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))TBA
LigandPNGBDBM50509088(CHEMBL4575427)
Affinity DataIC50:  3.79E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))TBA
LigandPNGBDBM50509085(TAUROACIDIN A)
Affinity DataIC50:  3.79E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50509088(CHEMBL4575427)
Affinity DataIC50:  4.46E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50509085(TAUROACIDIN A)
Affinity DataIC50:  4.46E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50509084(CHEMBL4531006)
Affinity DataIC50:  9.85E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337299(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337300(1-benzyl-3-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337301(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337303(1-(4-tert-butylbenzyl)-3-(3-(2-(2-hydroxy-2-(8-hyd...)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337298(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337297(1-Adamantan-1-ylmethyl-3-(3-{2-[2-hydroxy-2-(8-hyd...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337296(1-(biphenyl-2-yl)-3-(3-(2-(2-hydroxy-2-(8-hydroxy-...)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337295(1-benzhydryl-3-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337294(1-(2,6-dichlorobenzyl)-3-(3-(2-(2-hydroxy-2-(8-hyd...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337293(1-(4-fluorobenzyl)-3-(3-(2-(2-hydroxy-2-(8-hydroxy...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337292(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337302(3-((3-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihy...)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337291(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337301(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50:  0.0900nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337300(1-benzyl-3-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337299(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50:  0.0700nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)
Affinity DataEC50:  2.31E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337298(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337297(1-Adamantan-1-ylmethyl-3-(3-{2-[2-hydroxy-2-(8-hyd...)
Affinity DataEC50:  296nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337296(1-(biphenyl-2-yl)-3-(3-(2-(2-hydroxy-2-(8-hydroxy-...)
Affinity DataEC50:  5.77E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337295(1-benzhydryl-3-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo...)
Affinity DataEC50:  8.89E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337294(1-(2,6-dichlorobenzyl)-3-(3-(2-(2-hydroxy-2-(8-hyd...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337293(1-(4-fluorobenzyl)-3-(3-(2-(2-hydroxy-2-(8-hydroxy...)
Affinity DataEC50:  6.30E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337291(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337292(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50:  550nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed