TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 0.700nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 1.20nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 2.60nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 2.60nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 2.60nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 2.70nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 3nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 3nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 3.60nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 3.80nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 3.90nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 4nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 4.10nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 4.70nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human ChemR23 expressed in CAL-1 cells assessed as reduction in chemerin-induced calcium signalingMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 4.80nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 5nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/delta(Rattus norvegicus (Rat))
Kyowa Hakko Kirin
US Patent
Kyowa Hakko Kirin
US Patent
Affinity DataIC50: 5.20nMT: 2°CAssay Description:A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff...More data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human ChemR23 expressed in CAL-1 cells assessed as reduction in chemerin-induced calcium signalingMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human ChemR23 expressed in CAL-1 cells assessed as reduction in chemerin-induced calcium signalingMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human ChemR23 expressed in CAL-1 cells assessed as reduction in chemerin-induced calcium signalingMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human ChemR23 expressed in CAL-1 cells assessed as reduction in chemerin-induced calcium signalingMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based C...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as inhibition of chemerin-induced intracellular calcium ion concentration preincubated for 45 mins...More data for this Ligand-Target Pair