Affinity DataIC50: 0.240nMAssay Description:Inhibition of matrix metalloprotease-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.870nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.970nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against MMP-8More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Rattus norvegicus)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration of the compound against rat TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against human matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against MMP-2More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against MMP-3More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair