TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human PDE4A4 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human PDE4A4 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibition of human PDE4A4 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.690nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human PDE4A4 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.910nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of PDE4A4 expressed in yeastMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human PDE4A4 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE4A4 expressed in yeastMore data for this Ligand-Target Pair