TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 3.60E+3nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 2.20E+4nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 2.50E+5nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 9.00E+5nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: >3.20E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: >4.00E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (3'processing)More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of wild-type Staphylococcus aureus DNA gyrase assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophoresis ass...More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of wild-type Staphylococcus aureus DNA gyrase assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophoresis ass...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild-type Staphylococcus aureus DNA gyrase assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophoresis ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of wild-type Staphylococcus aureus DNA gyrase assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophoresis ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration of the compound was determined against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase by supercoiling assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase by supercoiling assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase by supercoiling assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase Ser84Leu mutant assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophores...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase by supercoiling assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase Ser84Leu mutant assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophores...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postass...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postasse...More data for this Ligand-Target Pair