Affinity DataKi: 6.5nMAssay Description:Evaluated for beta-receptor affinity determined in rat brain membrane fraction with [3H]- dihydroalprenololMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Evaluated for beta-receptor affinity determined in rat brain membrane fraction with [3H]- dihydroalprenololMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Evaluated for beta-receptor affinity, determined in rat brain membrane fraction with [3H]- dihydroalprenololMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Evaluated for beta-receptor affinity, determined in rat brain membrane fraction with [3H]- dihydroalprenololMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Evaluated for beta-receptor affinity, determined in rat brain membrane fraction with [3H]- dihydroalprenololMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Evaluated for beta-receptor affinity, determined in rat brain membrane fraction with [3H]- dihydroalprenololMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataKi: 1.56E+5nMAssay Description:Ability to inhibit the incorporation of dATP into DNA by DNA polymerase alphaMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataKi: 5.48E+5nMAssay Description:Ability to inhibit the incorporation of dATP into DNA by DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+5nMpH: 8.0Assay Description:Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate.More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+5nMpH: 8.0Assay Description:Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >0.0100nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0158nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0158nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0158nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of rat PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human PDE4D using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human PDE4D using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0251nMAssay Description:Inhibition of rat PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0251nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0251nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0251nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0251nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0251nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0316nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0316nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0316nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0316nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0316nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0316nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0316nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0398nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0398nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0501nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0501nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0501nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0501nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0631nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0631nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0631nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0794nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.0794nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysisMore data for this Ligand-Target Pair