TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0180nMAssay Description:Inhibition of human Nav 1.7 channel by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.111nMAssay Description:Inhibition of human Nav 1.7 channel by electrophysiologyMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Compound was evaluated for inhibition of binding of [3H]-C18 PAF to human platelet membrane Platelet activating factor receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:In vitro effect on inhibition of the binding of [3H]C18-Platelet activating factor to human PMN membranes preparationMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:In vitro effect on inhibition of the binding of [3H]C18-Platelet activating factor to human PMN membranes preparationMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:In vitro effect on inhibition of the binding of [3H]C18-Platelet activating factor to human PMN membranes preparationMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
Affinity DataKi: 3.72nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro inhibition of [3H]-C18 PAF binding to human platelet membrane Platelet activating factor receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]-RTX from human TRPV1 transfected in HEK293 cells after 60 mins by scintillation spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of human Nav 1.7 channel by electrophysiologyMore data for this Ligand-Target Pair
Affinity DataKi: 14.3nMAssay Description:In vitro inhibition of [3H]-C18 PAF binding to human platelet membrane Platelet activating factor receptor was determinedMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of human Nav 1.7 channel by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to human Nav1.7More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Binding affinity at human inactive state Nav1.7 by whole cell electrophysiologyMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparationMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel electrophysiology in inactivated state expressed in HEK293 cells using Voltage/Ion Probe Re...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel electrophysiology in inactivated state expressed in HEK293 cells using Voltage/Ion Probe Re...More data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:In vitro effect on inhibition of the binding of [3H]C18-Platelet activating factor to human PMN membranes preparationMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of human Nav1.7 by VIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Inhibition of human Nav1.7 by VIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Binding affinity to human Nav1.7More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair