Compile Data Set for Download or QSAR
maximum 50k data
Found 2342 with Last Name = 'patil' and Initial = 's'
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053851((3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-2H-quinoli...)
Affinity DataKi:  0.0940nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053800((1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-2H-q...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053865((3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-1H-isoquin...)
Affinity DataKi:  0.190nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053813((1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-1H-i...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053851((3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-2H-quinoli...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053813((1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-1H-i...)
Affinity DataKi:  0.220nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053800((1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-2H-q...)
Affinity DataKi:  0.260nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053865((3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-1H-isoquin...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053851((3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-2H-quinoli...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053800((1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-2H-q...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Jain University

Curated by ChEMBL
LigandPNGBDBM50276880(CHEMBL4171598)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Jain University

Curated by ChEMBL
LigandPNGBDBM50276880(CHEMBL4171598)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50018235(5-Amino-2-{4-[(2,4-diamino-5-chloro-quinazolin-6-y...)
Affinity DataKi:  1.70nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Jain University

Curated by ChEMBL
LigandPNGBDBM50276892(CHEMBL4167943)
Affinity DataKi:  3nMAssay Description:Inhibition of [125I]2-(3'-Iodo-4'-N-methylaminophenyl) benzothiazole binding to amyloid beta (1 to 40) (unknown origin) after 3 hrs by NaI well count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Jain University

Curated by ChEMBL
LigandPNGBDBM50276892(CHEMBL4167943)
Affinity DataKi:  3.70nMAssay Description:Antagonist activity at ER in human Ishikawa cells assessed as inhibition of E2-induced alkaline phosphatase induction after 72 hrs by PNPP substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Jain University

Curated by ChEMBL
LigandPNGBDBM50276883(CHEMBL4175800)
Affinity DataKi:  4.30nMAssay Description:Antagonist activity at ER in human MCF7 cells assessed as inhibition of 17beta-estradiol-induced cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Jain University

Curated by ChEMBL
LigandPNGBDBM50276883(CHEMBL4175800)
Affinity DataKi:  4.31nMAssay Description:Inhibition of [125I]2-(3'-Iodo-4'-N-methylaminophenyl) benzothiazole binding to amyloid beta (1 to 40) (unknown origin) after 3 hrs by NaI well count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053813((1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-1H-i...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042397(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  5.70nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053865((3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-1H-isoquin...)
Affinity DataKi:  8nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002472(5-Amino-2-{4-[(2-amino-5-chloro-4-oxo-3,4-dihydro-...)
Affinity DataKi:  8.30nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042397(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  8.5nMAssay Description:Inhibitory activity of alpha-keto esters towards calpain 1 at pH 8.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50276901(CHEMBL4167219)
Affinity DataKi:  9nMAssay Description:Inhibition of human erythrocytes mu-calpain using SucLeu-Tyr-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053850(CHEMBL130506 | {1-[1-(2-Hydroxy-2-phenyl-ethylamin...)
Affinity DataKi:  15nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053809(CHEMBL130114 | {3-Methyl-1-[1-(pyridin-2-ylmethyl)...)
Affinity DataKi:  17nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042403(CHEMBL325223 | [3-Methyl-1-(1-octylaminooxalyl-pro...)
Affinity DataKi:  19nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053822(CHEMBL132586 | Calpain XII | {3-Methyl-1-[1-(pyrid...)
Affinity DataKi:  19nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042423(CHEMBL325401 | [1-(1-Aminooxalyl-propylcarbamoyl)-...)
Affinity DataKi:  19nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042395(CHEMBL117336 | [3-Methyl-1-(1-phenethylaminooxalyl...)
Affinity DataKi:  22nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053794(CHEMBL335293 | {1-[1-(3,5-Dimethoxy-benzylaminooxa...)
Affinity DataKi:  22nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042395(CHEMBL117336 | [3-Methyl-1-(1-phenethylaminooxalyl...)
Affinity DataKi:  22nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042387(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  22nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042427(CHEMBL118025 | [1-(1-Benzylaminooxalyl-propylcarba...)
Affinity DataKi:  22nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053793((1-{1-Benzyl-2-oxo-2-[(quinolin-2-ylmethyl)-carbam...)
Affinity DataKi:  23nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042411(CHEMBL331850 | [1-(1-Benzyl-2-oxo-2-phenethylcarba...)
Affinity DataKi:  24nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042411(CHEMBL331850 | [1-(1-Benzyl-2-oxo-2-phenethylcarba...)
Affinity DataKi:  24nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042393(CHEMBL432443 | [1-(1-Benzyl-2-butylcarbamoyl-2-oxo...)
Affinity DataKi:  28nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053847((1-{1-[2-(1H-Indol-3-yl)-ethylaminooxalyl]-propylc...)
Affinity DataKi:  31nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053864(CHEMBL424074 | {1-[1-(Furan-2-ylmethyl)-aminooxaly...)
Affinity DataKi:  33nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042412(CHEMBL420872 | [1-(1-Benzyl-2-ethylcarbamoyl-2-oxo...)
Affinity DataKi:  39nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042412(CHEMBL420872 | [1-(1-Benzyl-2-ethylcarbamoyl-2-oxo...)
Affinity DataKi:  39nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053849(CHEMBL134002 | {3-Methyl-1-[1-(3-morpholin-4-yl-pr...)
Affinity DataKi:  41nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042414(CHEMBL119622 | {3-Methyl-1-[1-(3-phenyl-propylamin...)
Affinity DataKi:  43nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042414(CHEMBL119622 | {3-Methyl-1-[1-(3-phenyl-propylamin...)
Affinity DataKi:  43nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042422(CHEMBL117888 | {1-[1-(Cyclohexylmethyl-aminooxalyl...)
Affinity DataKi:  44nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042422(CHEMBL117888 | {1-[1-(Cyclohexylmethyl-aminooxalyl...)
Affinity DataKi:  44nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053838((1-{1-[2-(4-Methoxy-phenyl)-ethylaminooxalyl]-prop...)
Affinity DataKi:  46nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042408(CHEMBL419590 | [1-(1-Benzyl-2-benzylcarbamoyl-2-ox...)
Affinity DataKi:  46nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042408(CHEMBL419590 | [1-(1-Benzyl-2-benzylcarbamoyl-2-ox...)
Affinity DataKi:  46nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053847((1-{1-[2-(1H-Indol-3-yl)-ethylaminooxalyl]-propylc...)
Affinity DataKi:  50nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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