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Found 21 with Last Name = 'perez' and Initial = 'cj'
TargetCytochrome P450 2D6(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataIC50:  4.00E+3nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataIC50:  8.10E+3nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataIC50:  9.00E+3nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataIC50:  9.80E+3nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataIC50:  1.20E+4nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataIC50:  2.00E+4nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataIC50: >2.00E+4nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataIC50:  2.00E+4nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50266776(CHEMBL4066553)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsome using testosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataIC50: >2.00E+4nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataIC50: >2.00E+4nMT: 2°CAssay Description:Inhibition of hepatic cytochromes P450 was assessed in human liver microsomes using a substrate-specific approach of monitoring metabolites formed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50556552(CHEMBL583256)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsome using testosterone as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM213824(Posaconazole)
Affinity DataKd:  18nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM213825(VNI)
Affinity DataKd:  15nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPutative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataKd:  156nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPutative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataKd:  419nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataKd:  19nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataKd:  69nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataKd:  26nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataKd:  32nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPutative lanosterol 14-alpha-demethylase(Leishmania infantum)
Vanderbilt University

LigandPNGBDBM213824(Posaconazole)
Affinity DataKd:  18nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed