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Found 521 with Last Name = 'perveen' and Initial = 's'
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222435(N'',N'''-Bis[(E)-(2,6-dichlorophenyl)methylide...)
Affinity DataKi:  1.78E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222429(N'',N'''-Bis[(E)-(2-nitrophenyl)methylidene]ca...)
Affinity DataKi:  1.81E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222428(N'',N'''-Bis[(E)-(4-nitrophenyl)methylidene]ca...)
Affinity DataKi:  2.35E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222431(N'',N'''-Bis[(E)-(4-bromophenyl)methylidene]ca...)
Affinity DataKi:  2.52E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222139(Chymostatin | US11859014, Compound chymostatin)
Affinity DataKi:  2.60E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222430(N'',N'''-Bis[(E)-(2-chloro-5-nitrophenyl)methy...)
Affinity DataKi:  3.58E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222433(N'',N'''-Bis[(E)-(2-chlorophenyl)methylidene]c...)
Affinity DataKi:  4.12E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-...)
Affinity DataKi:  4.70E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448175(CHEMBL3120552)
Affinity DataKi:  8.60E+3nMAssay Description:Competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50077011(2-Phenyl-4H-3,1-benzoxazin-4-one (3) | 2-Phenyl-be...)
Affinity DataKi:  8.70E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50289006(2-(2-Bromo-phenyl)-benzo[d][1,3]oxazin-4-one | 2-(...)
Affinity DataKi:  9.10E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222117(2-(2-Thienyl)-4H-3,1-benzoxazin-4-one (4) | US1158...)
Affinity DataKi:  9.10E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222124(2-(2-Methylphenyl)-4H-3,1-benzoxazin-4-one (13))
Affinity DataKi:  9.80E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448176(CHEMBL3120570)
Affinity DataKi:  1.17E+4nMAssay Description:Competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448174(CHEMBL3120548)
Affinity DataKi:  1.21E+4nMAssay Description:Non-competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50289000(2-(2-Methoxy-phenyl)-benzo[d][1,3]oxazin-4-one | 2...)
Affinity DataKi:  1.25E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222118(2-(4-Methoxyphenyl)-4H-3,1-benzoxazin-4-one (5))
Affinity DataKi:  1.26E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448177(CHEMBL1576403)
Affinity DataKi:  1.56E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448178(CHEMBL3120574)
Affinity DataKi:  1.57E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222121(2-(3-Methylphenyl)-4H-3,1-benzoxazin-4-one (10))
Affinity DataKi:  1.61E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222119(2-(4-Methylphenyl)-4H-3,1-benzoxazin-4-one (7))
Affinity DataKi:  1.64E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448179(CHEMBL1544729)
Affinity DataKi:  1.68E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222123(2-(3-Fluorophenyl)-4H-3,1-benzoxazin-4-one (12))
Affinity DataKi:  1.78E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448184(CHEMBL3120558)
Affinity DataKi:  1.81E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448182(CHEMBL3120560)
Affinity DataKi:  1.81E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448180(CHEMBL3120571)
Affinity DataKi:  1.85E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448185(CHEMBL3120566)
Affinity DataKi:  1.93E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50229993(2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...)
Affinity DataKi:  2.00E+4nMAssay Description:Competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM33703(2-(2-Nitro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-(...)
Affinity DataKi:  2.24E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222125(2-(3-Chlorophenyl)-4H-3,1-benzoxazin-4-one (14))
Affinity DataKi:  2.26E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50018905(2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  2.50E+4nMAssay Description:Non-competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl alpha-D-glucopyranoside as substrate preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222122(2-(2,6-Dimethoxyphenyl)-4H-3,1-benzoxazin-4-one (1...)
Affinity DataKi:  2.77E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222120(2-(2,6-Difluorophenyl)-4H-3,1-benzoxazin-4-one (8))
Affinity DataKi:  3.01E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50074020(CHEMBL1099206)
Affinity DataKi:  6.80E+4nMAssay Description:Competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl alpha-D-glucopyranoside as substrate preincubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222127(2-(4-Fluorophenyl)-4H-3,1-benzoxazin-4-one (16))
Affinity DataKi:  9.41E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304608(5,5'-(propane-1,3-diyl)bis(1,3,4-oxadiazole-2(3H)-...)
Affinity DataKi:  1.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222126(2-(3-Methylphenyl)-7-nitro-4H-3,1-benzoxazin-4-one...)
Affinity DataKi:  1.62E+5nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222128(7-Chloro-2-(2-fluorophenyl)-4H-3,1-benzoxazin-4-on...)
Affinity DataKi:  3.03E+5nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50449429(2-(3-Nitrophenyl)-4H-3,1-benzoxazin-4-one (18) | C...)
Affinity DataKi:  3.41E+5nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304607(5-(3-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...)
Affinity DataKi:  3.60E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304609(5-[4-t-Butyldimethylsilyloxy phenyl]-1,3,4-oxadiaz...)
Affinity DataKi:  3.60E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304606(5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...)
Affinity DataKi:  8.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304605(5-(4-hydroxyphenyl)-1,3,4-thiadiazole-2(3H)-thione...)
Affinity DataKi:  8.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50532145(CHEMBL1549559)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Escherichia coli)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM50284071(CHEMBL4165927)
Affinity DataIC50:  100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM50284029(CHEMBL4168635)
Affinity DataIC50:  100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM50284055(CHEMBL4177204)
Affinity DataIC50:  200nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM50284072(CHEMBL4173852)
Affinity DataIC50:  300nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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