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Found 226 with Last Name = 'peterson' and Initial = 'tl'
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi:  6.30E+3nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi:  9.42E+3nMAssay Description:Binding affinity to chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to factor IXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi: >1.40E+4nMAssay Description:Binding affinity to urokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity to tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi: >1.94E+4nMAssay Description:Binding affinity to plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi: >2.15E+4nMAssay Description:Binding affinity to activated protein CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi: >2.20E+4nMAssay Description:Binding affinity to plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataKi: >5.50E+4nMAssay Description:Binding affinity to factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392514(CHEMBL2152167)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392527(CHEMBL2152180)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392530(CHEMBL2152183)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392513(CHEMBL2152166)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392528(CHEMBL2152181)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392504(CHEMBL2152158)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392515(CHEMBL2152168)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392517(CHEMBL2152170)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392526(CHEMBL2152179)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392522(CHEMBL2152175)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175075((S,Z)-4-hydroxybutyl 2-cyano-3-(2-methylbenzofuran...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175078((S,Z)-3-(1-(2-methylbenzofuran-5-ylamino)-3-oxo-3-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392516(CHEMBL2152169)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376718(CHEMBL261502)
Affinity DataIC50:  10nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376712(CHEMBL259502)
Affinity DataIC50:  11nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175097((S,Z)-1-(2-cyano-3-(2-methylbenzofuran-5-ylamino)-...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175093((S,Z)-2-(4-chlorobenzoyl)-3-(2-methylbenzofuran-5-...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175076((S,Z)-2-(4-methoxybenzoyl)-3-(2-methylbenzofuran-5...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376713(CHEMBL259710)
Affinity DataIC50:  15nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175095((S,Z)-2-cyano-3-(2-methylbenzofuran-5-ylamino)-3-(...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376711(CHEMBL259503)
Affinity DataIC50:  18nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376719(CHEMBL258795)
Affinity DataIC50:  18nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175079((S,Z)-methyl 2-cyano-3-(2-methylbenzofuran-5-ylami...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392499(CHEMBL2152152)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392507(CHEMBL2152162)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376693(CHEMBL409318)
Affinity DataIC50:  23nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175081((S,Z)-ethyl 2-cyano-3-(2-methylbenzofuran-5-ylamin...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392529(CHEMBL2152182)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM26351(2-methylbenzofuran compound, 2 | 2-{[(2-methyl-1-b...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376694(CHEMBL261062)
Affinity DataIC50:  31nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)
Affinity DataIC50:  36nMAssay Description:Inhibition of CETP in human whole plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376715(CHEMBL264963)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376716(CHEMBL264964)
Affinity DataIC50:  42nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175080((S,Z)-3-(2-methylbenzofuran-5-ylamino)-2-(methylsu...)
Affinity DataIC50:  46nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50376724(CHEMBL407147)
Affinity DataIC50:  49nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392525(CHEMBL2152178)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392501(CHEMBL2152154)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175083((S,Z)-3-(1-(2-methylbenzofuran-5-ylamino)-2-nitrov...)
Affinity DataIC50:  51nMAssay Description:Inhibitory activity against human FXaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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