Compile Data Set for Download or QSAR
maximum 50k data
Found 110 with Last Name = 'pham' and Initial = 'q'
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243005(2-(6-Chloro-2-(4-(2-fluoroethoxy)phenyl)imidazo[1,...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243006(2-(6-Chloro-2-(4-(3-fluoropropoxy)phenyl)imidazo[1...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243008(CHEMBL469682 | N,N-Diethyl-2-(2-(4-(3-fluoropropox...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243006(2-(6-Chloro-2-(4-(3-fluoropropoxy)phenyl)imidazo[1...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243007(2-(2-(4-(2-Fluoroethoxy)phenyl)-5,7-dimethylpyrazo...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243007(2-(2-(4-(2-Fluoroethoxy)phenyl)-5,7-dimethylpyrazo...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243008(CHEMBL469682 | N,N-Diethyl-2-(2-(4-(3-fluoropropox...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243005(2-(6-Chloro-2-(4-(2-fluoroethoxy)phenyl)imidazo[1,...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217008(CHEMBL230904 | N-(1-(2-fluoroethyl)piperidin-4-yl)...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217012(CHEMBL231120 | N-(4-(2-azanorborn-2-yl)butyl)-4-io...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217015(CHEMBL231119 | N-(1-(2-hydroxyethyl)piperidin-4-yl...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217014(CHEMBL230903 | N-(2-(diethylamino)ethyl)-5-iodo-2-...)
Affinity DataKi:  650nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217009(4-acetamido-N-(4-(2-azanorborn-2-yl)butyl)-5-iodo-...)
Affinity DataKi:  680nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217013(CHEMBL230692 | N-(2-(diethylamino)ethyl)-5-iodo-2-...)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217018(CHEMBL395005 | N-(4-(dipropylamino)butyl)-4-iodobe...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217010(4-acetamido-N-(4-(N-butyl-N-methylamino)butyl)-5-i...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50092740(4-Acetylamino-N-(2-diethylamino-ethyl)-5-iodo-2-me...)
Affinity DataKi:  1.65E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217011(4-acetamido-N-(4-(butylamino)butyl)-5-iodo-2-metho...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217016(4-acetamido-N-(4-(N-isopropyl-N-methylamino)butyl)...)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418183(CHEMBL1761688)
Affinity DataKi:  6.31E+3nMAssay Description:Displacement of labeled-dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217017(4-acetamido-N-(4-(dipropylamino)butyl)-5-iodo-2-me...)
Affinity DataKi:  7.80E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336144((1R,3S)-4-chloro-N-(3-hydroxycyclohexyl)-5-(4-(tri...)
Affinity DataIC50:  0.501nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418961(CHEMBL1807877)
Affinity DataIC50:  0.631nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418959(CHEMBL1807875)
Affinity DataIC50:  0.631nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299378(CHEMBL575340 | N4-(2,3-dihydro-1H-inden-2-yl)-2-(p...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418981(CHEMBL1807878)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336144((1R,3S)-4-chloro-N-(3-hydroxycyclohexyl)-5-(4-(tri...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418965(CHEMBL1807883)
Affinity DataIC50:  3.16nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418964(CHEMBL1807882)
Affinity DataIC50:  3.98nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418960(CHEMBL1807876)
Affinity DataIC50:  5.01nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299360(CHEMBL575741 | N2-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336143((1S,3R)-4-chloro-N-(3-hydroxycyclohexyl)-5-(4-(tri...)
Affinity DataIC50:  7.40nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299366(4-(2,3-dihydro-1H-inden-2-yloxy)-6-(piperazin-1-yl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299374((R)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(3-methylpipe...)
Affinity DataIC50:  8nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299372(6-(1,4-diazepan-1-yl)-N2-(2,3-dihydro-1H-inden-2-y...)
Affinity DataIC50:  11nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299378(CHEMBL575340 | N4-(2,3-dihydro-1H-inden-2-yl)-2-(p...)
Affinity DataIC50:  12nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418963(CHEMBL1807881)
Affinity DataIC50:  12.6nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418979(CHEMBL1807879)
Affinity DataIC50:  12.6nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299379(CHEMBL578643 | N4-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  14nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336162(4-chloro-N-cyclopentyl-5-(4-(trifluoromethyl)pheny...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299372(6-(1,4-diazepan-1-yl)-N2-(2,3-dihydro-1H-inden-2-y...)
Affinity DataIC50:  17nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418973(CHEMBL1807958)
Affinity DataIC50:  19.9nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336140((1R,3S)-4-chloro-N-(3-hydroxycyclopentyl)-5-(4-(tr...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299364(6-(piperazin-1-yl)-N2-(pyridin-4-yl)-N4-(1,2,3,4-t...)
Affinity DataIC50:  23nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299374((R)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(3-methylpipe...)
Affinity DataIC50:  26nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299360(CHEMBL575741 | N2-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418984(CHEMBL1807959)
Affinity DataIC50:  39.8nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336136(4-chloro-N-(tetrahydro-2H-pyran-4-yl)-5-(4-(triflu...)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336159(4-bromo-N-cyclopentyl-5-(4-(trifluoromethyl)phenyl...)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336147(CHEMBL1669535 | cis-(+/-)-4-chloro-N-(2-(hydroxyme...)
Affinity DataIC50:  48nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 110 total ) | Next | Last >>
Jump to: