Compile Data Set for Download or QSAR
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Found 166 with Last Name = 'phelan' and Initial = 'km'
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188272(7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...)
Affinity DataIC50:  103nMAssay Description:Inhibition of cKit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188266(7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  145nMAssay Description:Inhibition of cKit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188272(7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...)
Affinity DataIC50:  169nMAssay Description:Inhibition of FLT4 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188266(7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  180nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188272(7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...)
Affinity DataIC50:  293nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175237(CHEMBL199528 | N-butyl-N-methyl-3-phenyl-1H-thieno...)
Affinity DataIC50:  350nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188283(6-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  400nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175239(CHEMBL199755 | N-cyclohexyl-3-phenyl-1H-thieno[2,3...)
Affinity DataIC50:  490nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175247(CHEMBL200499 | N-benzyl-3-phenyl-1H-thieno[2,3-c]p...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188281(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroi...)
Affinity DataIC50:  500nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175241(CHEMBL199383 | N-(4-methoxybenzyl)-3-phenyl-1H-thi...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188290(7-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...)
Affinity DataIC50:  600nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188272(7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...)
Affinity DataIC50:  601nMAssay Description:Inhibition of FLT1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188275(6-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...)
Affinity DataIC50:  700nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188292(3-(thiophen-2-yl)-1,4-dihydroindeno[1,2-c]pyrazole...)
Affinity DataIC50:  930nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188266(7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  970nMAssay Description:Inhibition of FLT1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188271(6-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-2-y...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188284(3-phenyl-1,4-dihydroindeno[1,2-c]pyrazole | CHEMBL...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188269(3-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1,4-d...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188266(7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of FLT4 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175234(CHEMBL197923 | N-phenethyl-3-phenyl-1H-thieno[2,3-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188277(6-((4-methylpiperazin-1-yl)methyl)-3-(thiazol-5-yl...)
Affinity DataIC50:  2.84E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188289(3-(3-((4-methylpiperazin-1-yl)methyl)phenyl)-1,4-d...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175232((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188273(6-((4-methylpiperazin-1-yl)methyl)-3-(5-methylthio...)
Affinity DataIC50:  5.47E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175246(3-methyl-4-(thiophene-2-carboxamido)-1H-thieno[2,3...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188274(6-((4-methylpiperazin-1-yl)methyl)-3-(thiazol-4-yl...)
Affinity DataIC50:  7.48E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175235(4-(2-chlorobenzamido)-3-methyl-1H-thieno[2,3-c]pyr...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175250(CHEMBL370199 | methyl 2-(5-carbamoyl-3-methyl-1H-t...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against Plk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175245(1-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyrazol-4-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibitory activity against Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188279(6-((4-methylpiperazin-1-yl)methyl)-3-(pyridin-3-yl...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175239(CHEMBL199755 | N-cyclohexyl-3-phenyl-1H-thieno[2,3...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against CDK2/Cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175252(3-methyl-4-(2-phenoxyacetamido)-1H-thieno[2,3-c]py...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175239(CHEMBL199755 | N-cyclohexyl-3-phenyl-1H-thieno[2,3...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against Plk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175243(CHEMBL373001 | N-benzyl-3-methyl-1H-thieno[2,3-c]p...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188265(6-((4-methylpiperazin-1-yl)methyl)-3-(4-methylthio...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175245(1-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyrazol-4-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory activity against Pak4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188268(5-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175247(CHEMBL200499 | N-benzyl-3-phenyl-1H-thieno[2,3-c]p...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity against Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175243(CHEMBL373001 | N-benzyl-3-methyl-1H-thieno[2,3-c]p...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against Plk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175241(CHEMBL199383 | N-(4-methoxybenzyl)-3-phenyl-1H-thi...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175251(CHEMBL200796 | methyl 3-(phenylamino)-1H-thieno[2,...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175249(CHEMBL371242 | N-butyl-3-methyl-1H-thieno[2,3-c]py...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188287(6-((4-methylpiperazin-1-yl)methyl)-3-(thiazol-2-yl...)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175250(CHEMBL370199 | methyl 2-(5-carbamoyl-3-methyl-1H-t...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175234(CHEMBL197923 | N-phenethyl-3-phenyl-1H-thieno[2,3-...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against Plk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175247(CHEMBL200499 | N-benzyl-3-phenyl-1H-thieno[2,3-c]p...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175246(3-methyl-4-(thiophene-2-carboxamido)-1H-thieno[2,3...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50175238(3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide | ...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188272(7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of Tie2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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