Affinity DataKi: 0.0200nMAssay Description:Inhibition of fluorescein labeled probe binding to His-tagged human TYK2 pseudokinase domain (575-869 residues) by Morrison titration based HTRF assa...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Binding affinity for matrix metalloproteinase 13More data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Binding affinity for matrix metalloproteinase 13More data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Binding affinity for matrix metalloproteinase 13More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.720nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.720nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataKi: 0.950nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pri
Curated by ChEMBL
Bristol-Myers Squibb Pri
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibitory activity of the compound against IMPDH II with respect to IMP and NADMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair