Compile Data Set for Download or QSAR
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Found 65 with Last Name = 'polsky-fisher' and Initial = 's'
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248064(2,4-dichloro-N-((4-(2-hydroxycyclohexyl)-1-(propyl...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248062(2,4-dichloro-N-((1-(propylsulfonyl)-4-((tetrahydro...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248100((2,4-dichloro-N-((1-(propylsulfonyl)-4-(pyridin-2-...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248128(2,4-dichloro-N-((1-(2-fluoropropylsulfonyl)-4-(pyr...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50167083(CHEMBL3800482)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50167086(CHEMBL3798212)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50167074(CHEMBL3799913)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248097(2-(4-((2,4-dichlorobenzamido)methyl)-1-(propylsulf...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50167084(CHEMBL3798524)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248063(2,4-dichloro-N-((4-(2-methoxyethyl)-1-(propylsulfo...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50167085(CHEMBL3799623)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248099(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(propylsu...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167084(CHEMBL3798524)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248098(CHEMBL462148 | N-((4-(azetidin-1-yl)-1-(propylsulf...)
Affinity DataIC50:  38nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167074(CHEMBL3799913)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167085(CHEMBL3799623)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167078(CHEMBL3800198)
Affinity DataIC50:  55nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248130(2,4-dichloro-N-((1-(ethylsulfonyl)-4-(pyridin-2-yl...)
Affinity DataIC50:  57nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248162(2,4-dichloro-N-((1-(N,N-dimethylsulfamoyl)-4-(pyri...)
Affinity DataIC50:  77nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167083(CHEMBL3800482)
Affinity DataIC50:  84nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248127(2,4-dichloro-N-((1-(2-hydroxypropylsulfonyl)-4-(py...)
Affinity DataIC50:  86nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167086(CHEMBL3798212)
Affinity DataIC50:  101nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248159(CHEMBL463024 | N-((1-(butylsulfonyl)-4-(pyridin-2-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167079(CHEMBL3797723)
Affinity DataIC50:  128nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248160(2,4-dichloro-N-((1-(cyclopropylsulfonyl)-4-(pyridi...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248161(2,4-dichloro-N-((1-(isopropylsulfonyl)-4-(pyridin-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248129(2,4-dichloro-N-((1-(methylsulfonyl)-4-(pyridin-2-y...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167080(CHEMBL3798286)
Affinity DataIC50:  456nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167087(CHEMBL3798113)
Affinity DataIC50:  574nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167092(CHEMBL3797584)
Affinity DataIC50:  672nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167082(CHEMBL3797901)
Affinity DataIC50:  706nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167256(CHEMBL3798854)
Affinity DataIC50:  826nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167078(CHEMBL3800198)
Affinity DataIC50:  946nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167076(CHEMBL3797305)
Affinity DataIC50:  962nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248208(2,4-dichloro-N-((4-(pyridin-2-yl)-1-(2,2,2-trifluo...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167076(CHEMBL3797305)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167075(CHEMBL3799278)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167082(CHEMBL3797901)
Affinity DataIC50:  2.05E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167080(CHEMBL3798286)
Affinity DataIC50:  2.33E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167079(CHEMBL3797723)
Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167074(CHEMBL3799913)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248207(2,4-dichloro-N-((4-(pyridin-2-yl)-1-(trifluorometh...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167077(CHEMBL3797649)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167081(CHEMBL3798144)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167075(CHEMBL3799278)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167077(CHEMBL3797649)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167081(CHEMBL3798144)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248129(2,4-dichloro-N-((1-(methylsulfonyl)-4-(pyridin-2-y...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248128(2,4-dichloro-N-((1-(2-fluoropropylsulfonyl)-4-(pyr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50248099(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(propylsu...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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