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Found 133 with Last Name = 'potter' and Initial = 'ga'
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052668(Adamantane-1-carboxylic acid (S)-1-pyridin-4-yl-et...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031677((S)-13-Methyl-17-pyridin-3-yl-7,8,9,11,12,13,14,15...)
Affinity DataIC50:  1.80nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031666((10R,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,6,7,8...)
Affinity DataIC50:  2.10nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031669((3R,5S,10S,13S)-10,13-Dimethyl-17-pyridin-3-yl-2,3...)
Affinity DataIC50:  2.5nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031677((S)-13-Methyl-17-pyridin-3-yl-7,8,9,11,12,13,14,15...)
Affinity DataIC50:  2.60nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052669(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-4-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031666((10R,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,6,7,8...)
Affinity DataIC50:  2.80nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  2.90nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031665((10R,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,6,7,8,9...)
Affinity DataIC50:  2.90nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031676((5S,10S,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,4,...)
Affinity DataIC50:  3nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052668(Adamantane-1-carboxylic acid (S)-1-pyridin-4-yl-et...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  4nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031669((3R,5S,10S,13S)-10,13-Dimethyl-17-pyridin-3-yl-2,3...)
Affinity DataIC50:  4.30nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031676((5S,10S,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,4,...)
Affinity DataIC50:  4.70nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  5nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031667(3-((10R,13S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14...)
Affinity DataIC50:  5.60nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029237(2-Pyridin-4-yl-propionic acid (S)-2,6,6-trimethyl-...)
Affinity DataIC50:  6nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029237(2-Pyridin-4-yl-propionic acid (S)-2,6,6-trimethyl-...)
Affinity DataIC50:  6nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052669(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-4-...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029228(2-Pyridin-4-yl-butyric acid (S)-2,6,6-trimethyl-bi...)
Affinity DataIC50:  9nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029228(2-Pyridin-4-yl-butyric acid (S)-2,6,6-trimethyl-bi...)
Affinity DataIC50:  9nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029240(2-Methyl-2-pyridin-4-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031665((10R,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,6,7,8,9...)
Affinity DataIC50:  13nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029230(2-Methyl-2-pyridin-3-yl-propionic acid 2-methyl-ad...)
Affinity DataIC50:  13nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031667(3-((10R,13S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14...)
Affinity DataIC50:  13nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029229(2-Methyl-2-pyridin-3-yl-propionic acid adamantan-1...)
Affinity DataIC50:  13nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029229(2-Methyl-2-pyridin-3-yl-propionic acid adamantan-1...)
Affinity DataIC50:  13nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029241(2-Pyridin-3-yl-propionic acid (S)-2,6,6-trimethyl-...)
Affinity DataIC50:  14nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  14nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029242(2-Methyl-2-pyridin-3-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  15nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029242(2-Methyl-2-pyridin-3-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  15nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50407398(ABIRATERONE ACETATE | CB7630 | Zytiga)
Affinity DataIC50:  17nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50407398(ABIRATERONE ACETATE | CB7630 | Zytiga)
Affinity DataIC50:  18nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052671(Adamantane-1-carboxylic acid pyridin-4-ylmethyl es...)
Affinity DataIC50:  18nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031671((3S,10R,13S,17S)-10,13-Dimethyl-17-pyridin-3-yl-2,...)
Affinity DataIC50:  23nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029240(2-Methyl-2-pyridin-4-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  26nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  26nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  26nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029226(2-Pyridin-3-yl-propionic acid adamantan-1-yl ester...)
Affinity DataIC50:  35nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029236(2-Ethyl-2-pyridin-4-yl-butyric acid (S)-2,6,6-trim...)
Affinity DataIC50:  35nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029226(2-Pyridin-3-yl-propionic acid adamantan-1-yl ester...)
Affinity DataIC50:  35nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029227(CHEMBL135095 | Pyridin-3-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  38nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029227(CHEMBL135095 | Pyridin-3-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  38nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052671(Adamantane-1-carboxylic acid pyridin-4-ylmethyl es...)
Affinity DataIC50:  43nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031671((3S,10R,13S,17S)-10,13-Dimethyl-17-pyridin-3-yl-2,...)
Affinity DataIC50:  47nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029242(2-Methyl-2-pyridin-3-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  47nMAssay Description:Inhibition of rat testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029232(CHEMBL134442 | Pyridin-4-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  52nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029242(2-Methyl-2-pyridin-3-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  52nMAssay Description:Inhibition of rat testicular C17,20-LyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50031674((3S,10R,13S,17R)-10,13-Dimethyl-17-pyridin-4-yl-2,...)
Affinity DataIC50:  53nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  65nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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