Compile Data Set for Download or QSAR
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Found 313 with Last Name = 'powers' and Initial = 'm'
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000485((S)-2-(5-chlorospiro[2,3-dihydrobenzo[b]furan-2,1'...)
Affinity DataKi:  0.190nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000482((R)-2-(5-chlorospiro[2,3-dihydrobenzo[b]furan-2,1'...)
Affinity DataKi:  0.890nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000480(2-(5-chlorospiro[2,3-dihydrobenzo[b]furan-2,1'-cyc...)
Affinity DataKi:  1.10nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000479(7-Chloro-2,3,4,5-tetrahydro-benzo[b]oxepine-9-carb...)
Affinity DataKi:  1.20nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  1.5nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000495((ICS 205-930)1H-Indole-3-carboxylic acid 6-methyl-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000483((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
Affinity DataKi:  1.70nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000494(7-Bromo-2,3,4,5-tetrahydro-benzo[b]oxepine-9-carbo...)
Affinity DataKi:  2.20nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(CHEMBL501238 | N-{m-[R(+)-1]Ureaphenoxy}ethyldigly...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000487(8-Chloro-3,4,5,6-tetrahydro-2H-benzo[b]oxocine-10-...)
Affinity DataKi:  4.70nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000489(CHEMBL353993 | N-(1-Aza-bicyclo[2.2.2]oct-3-yl)-5-...)
Affinity DataKi:  6.10nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  6.20nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(CHEMBL501238 | N-{m-[R(+)-1]Ureaphenoxy}ethyldigly...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000478(2,3,4,5-Tetrahydro-benzo[b]oxepine-9-carboxylic ac...)
Affinity DataKi:  14nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50006878((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(CHEMBL442943 | N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-o...)
Affinity DataKi:  14.2nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000484(7-Chloro-2,2-dimethyl-2,3,4,5-tetrahydro-benzo[b]o...)
Affinity DataKi:  16nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  16.3nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50006878((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265494((R)-N-methyl-2-(1-(3-(3-(1-methyl-2-oxo-5-phenyl-2...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(CHEMBL442943 | N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-o...)
Affinity DataKi:  24.1nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPirin(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataKi:  28nMAssay Description:Inhibition of bisamide probe binding to pirin in human SKOV3 cells by SILAC-based quantitative mass spectrometry pull down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  29.4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265533(2-({[(1S,5R,13R,14S,17S)-9,17-dihydroxy-4-methyl-1...)
Affinity DataKi:  29.8nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000486(CHEMBL368992 | N-(1-Aza-bicyclo[2.2.2]oct-3-yl)-2-...)
Affinity DataKi: >30nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265533(2-({[(1S,5R,13R,14S,17S)-9,17-dihydroxy-4-methyl-1...)
Affinity DataKi:  40.7nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000488(CHEMBL171070 | N-(1-Aza-bicyclo[2.2.2]oct-3-yl)-5-...)
Affinity DataKi:  47nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265494((R)-N-methyl-2-(1-(3-(3-(1-methyl-2-oxo-5-phenyl-2...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(CHEMBL501238 | N-{m-[R(+)-1]Ureaphenoxy}ethyldigly...)
Affinity DataKi:  57nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000490(7-Chloro-2,3,4,5-tetrahydro-benzo[b]oxepine-9-carb...)
Affinity DataKi:  63nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  71nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  77nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000481(8-Amino-7-chloro-2,3,4,5-tetrahydro-benzo[b]oxepin...)
Affinity DataKi: >100nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPirin(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234079(CHEMBL4096048 | US9701664, Example 80)
Affinity DataKi:  190nMAssay Description:Inhibition of bisamide probe binding to pirin in human SKOV3 cells by SILAC-based quantitative mass spectrometry pull down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(CHEMBL442943 | N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-o...)
Affinity DataKi:  210nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(CHEMBL442943 | N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-o...)
Affinity DataKi:  223nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  260nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(CHEMBL501238 | N-{m-[R(+)-1]Ureaphenoxy}ethyldigly...)
Affinity DataKi:  356nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM48320(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Affinity DataKi:  995nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234074(CHEMBL4070633 | US9701664, Example 39)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human U20S cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234074(CHEMBL4070633 | US9701664, Example 39)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human U20S cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234073(CHEMBL4063330 | US9701664, Example 1)
Affinity DataIC50:  12nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234073(CHEMBL4063330 | US9701664, Example 1)
Affinity DataIC50:  12nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataIC50:  19nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataIC50:  19nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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