BindingDB PrimarySearch

Found 1219 with Last Name = 'prasad' and Initial = 'v'

Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM430(3-[(2-tert-butyl-4-hydroxy-5-methylphenyl)sulfanyl...)

Ki: 0.0300nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair

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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM430(3-[(2-tert-butyl-4-hydroxy-5-methylphenyl)sulfanyl...)

Ki: 0.0300nM ΔG°: -62.5kJ/molepH: 6.2 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair

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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM472(5-tert-butyl-4-{[(6S)-4-hydroxy-6-[2-(4-hydroxyphe...)

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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM50409174(CHEMBL169119)

Ki: 0.0300nMAssay Description:Tested for binding affinity against HIV proteaseMore data for this Ligand-Target Pair

PDB MMDB
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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM472(5-tert-butyl-4-{[(6S)-4-hydroxy-6-[2-(4-hydroxyphe...)

Ki: 0.0300nMAssay Description:Tested for binding affinity against HIV proteaseMore data for this Ligand-Target Pair

PDB MMDB
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CHEMBL PC cid PC sid Similars

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Adenosine receptor A2a(Rattus norvegicus (rat))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457085(CHEMBL4203542)

Ki: 0.0500nMAssay Description:Antagonist activity at rat A2A receptor assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 mins followed by CGS-21680 addition m...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Rattus norvegicus (rat))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457098(CHEMBL4217582)

Ki: 0.0600nMAssay Description:Antagonist activity at rat A2A receptor assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 mins followed by CGS-21680 addition m...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457098(CHEMBL4217582)

Ki: 0.0600nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM465((6S)-3-[(4-amino-2-tert-butyl-5-methylphenyl)sulfa...)

Ki: 0.0700nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair

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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM465((6S)-3-[(4-amino-2-tert-butyl-5-methylphenyl)sulfa...)

Ki: 0.0700nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair

PDB MMDB
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CHEMBL PC cid PC sid Similars

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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM465((6S)-3-[(4-amino-2-tert-butyl-5-methylphenyl)sulfa...)

Ki: 0.0700nMpH: 6.2Assay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair

PDB MMDB
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457084(CHEMBL4217248)

Ki: 0.0700nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM2208((6S)-3-{[2-tert-butyl-4-(hydroxymethyl)-5-methylph...)

Ki: 0.0900nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair

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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM2204((3-(2-tert-Butyl-4-hydroxymethyl-5-methyl-phenylsu...)

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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM50078088((S)-3-(2-tert-Butyl-4-hydroxymethyl-5-methyl-pheny...)

Ki: 0.0900nMpH: 6.2Assay Description:In vitro binding affinity of the compound against HIV protease at pH 6.2 was determinedMore data for this Ligand-Target Pair

PDB MMDB
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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM50078088((S)-3-(2-tert-Butyl-4-hydroxymethyl-5-methyl-pheny...)

Ki: 0.0900nMpH: 4.7Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 4.7More data for this Ligand-Target Pair

PDB MMDB
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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM50216785(CHEMBL61756)

Ki: <0.100nMpH: 4.7Assay Description:Inhibitory activity of the compound was evaluated against human immunodeficiency virus type 1(HIV-1) protease at pH 6.2More data for this Ligand-Target Pair

PDB MMDB
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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM50368427(CHEMBL1790880 | CHEMBL3349491)

Ki: 0.100nMAssay Description:Binding affinity to HIV proteaseMore data for this Ligand-Target Pair

PDB MMDB
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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM50078087((S)-6-[2-(4-Amino-phenyl)-ethyl]-3-(2-tert-butyl-4...)

Ki: 0.110nMpH: 6.2Assay Description:In vitro binding affinity of the compound against HIV protease at pH 6.2 was determinedMore data for this Ligand-Target Pair

PDB MMDB
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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM2206((6S)-6-[2-(4-aminophenyl)ethyl]-3-{[2-tert-butyl-4...)

Ki: 0.110nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457085(CHEMBL4203542)

Ki: 0.150nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM2533(3-{[2-tert-butyl-4-(hydroxymethyl)-5-methylphenyl]...)

Ki: 0.170nM ΔG°: -58.0kJ/molepH: 6.2 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair

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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM469(CHEMBL2110206 | Dihydropyran-2-one deriv. 74 | N-(...)

Ki: 0.200nMAssay Description:Tested for binding affinity against HIV proteaseMore data for this Ligand-Target Pair

PDB MMDB
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457093(CHEMBL4212821)

Ki: 0.200nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50235055(CHEMBL4095355)

Ki: 0.200nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in HEK293 cell membranes assessed as decrease in CGS-21680/forskolin-induced cAMP level...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM469(CHEMBL2110206 | Dihydropyran-2-one deriv. 74 | N-(...)

Ki: 0.200nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair

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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM402(CHEMBL354027 | Dihydropyran-2-one deriv. 7 | N-[5-...)

Ki: 0.210nMAssay Description:Tested for binding affinity against HIV proteaseMore data for this Ligand-Target Pair

PDB MMDB
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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM402(CHEMBL354027 | Dihydropyran-2-one deriv. 7 | N-[5-...)

Ki: 0.210nM ΔG°: -57.5kJ/molepH: 6.2 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457099(CHEMBL4213177)

Ki: 0.210nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457093(CHEMBL4212821)

Ki: 0.220nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM50368430(CHEMBL1790874 | CHEMBL3349485)

Ki: 0.240nMAssay Description:Binding affinity to HIV proteaseMore data for this Ligand-Target Pair

PDB MMDB
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457097(CHEMBL4205884)

Ki: 0.25nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50235053(CHEMBL4064207)

Ki: 0.25nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in HEK293 cell membranes assessed as decrease in CGS-21680/forskolin-induced cAMP level...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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CHEMBL PC cid PC sid Similars

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457092(CHEMBL4207914)

Ki: 0.260nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457103(CHEMBL4217668)

Ki: 0.270nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Rattus norvegicus (rat))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457087(CHEMBL4205341)

Ki: 0.280nMAssay Description:Antagonist activity at rat A2A receptor assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 mins followed by CGS-21680 addition m...More data for this Ligand-Target Pair

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50011294(A2A | Ro-4494351 | Ro-4494351-002 | Ro-4494351000 ...)

Ki: 0.300nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in HEK293 cell membranes assessed as decrease in CGS-21680/forskolin-induced cAMP level...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Purchase MCE
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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457092(CHEMBL4207914)

Ki: 0.300nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457097(CHEMBL4205884)

Ki: 0.300nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457105(CHEMBL4212278)

Ki: 0.300nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid

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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM470(CHEMBL2110205 | Dihydropyran-2-one deriv. 75 | N-(...)

Ki: 0.310nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair

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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM467((S)-N-(5-tert-Butyl-4-{4-hydroxy-6-[2-(4-hydroxyph...)

Ki: 0.390nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair

PDB
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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM467((S)-N-(5-tert-Butyl-4-{4-hydroxy-6-[2-(4-hydroxyph...)

Ki: 0.390nMAssay Description:Tested for binding affinity against HIV proteaseMore data for this Ligand-Target Pair

PDB MMDB
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CHEMBL PC cid PC sid Similars

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Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

BDBM50368420(CHEMBL1790890 | CHEMBL3349500)

Ki: 0.400nMAssay Description:Binding affinity to HIV proteaseMore data for this Ligand-Target Pair

PDB MMDB
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CHEMBL PC cid PC sid Similars

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457086(CHEMBL4215754)

Ki: 0.400nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457104(CHEMBL4217235)

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457091(CHEMBL4207104)

PDB MMDB NCI pathway Reactome pathway KEGG
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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457098(CHEMBL4217582)

Ki: 0.400nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457107(CHEMBL4209408)

Ki: 0.400nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Adenosine receptor A2a(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL

BDBM50457085(CHEMBL4203542)

Ki: 0.400nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 90 mins radioligand binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Displayed 1 to 50 (of 1219 total ) | Next | Last >>

Filter my 1219 hits

Targets 33▿
- Dimer of Gag-Pol polyprotein [489-587] 270
- Gag-Pol polyprotein [489-587] 240
- Dual specificity mitogen-activated protein kinase kinase 1 177
- Presenilin-1 139
- Adenosine receptor A2b 124
- Adenosine receptor A2a 116
- Tyrosine-protein phosphatase non-receptor type 1 22
- Adenosine receptor A1 20
- Reverse transcriptase 19
- 1-deoxy-D-xylulose 5-phosphate reductoisomerase 17
- Biotin carboxylase 14
- Caspase-1 8
- Amine oxidase [flavin-containing] A 7
- Isocitrate dehydrogenase [NADP] cytoplasmic 6
- Somatostatin receptor type 4 5
- Adenosine receptor A3 4
- Reverse transcriptase protein 3
- Receptor-type tyrosine-protein kinase FLT3 2
- Serine/threonine-protein kinase Chk2 2
- Somatostatin receptor type 2 2
- Cytochrome P450 1A2 2
- DNA gyrase subunit A 2
- Substance-P receptor 2
- Tyrosine-protein kinase receptor UFO 2
- Cytochrome P450 2C9 2
- Ribosomal protein S6 kinase beta-1/beta-2 2
- Cytochrome P450 2C19 2
- Aurora kinase A 2
- Cytochrome P450 2D6 2
- Tyrosine-protein phosphatase non-receptor type 2 1
- Nuclear receptor subfamily 1 group I member 2 1
- Potassium voltage-gated channel subfamily H member 2 1
- Cytochrome P450 3A4 1
- ...
Publications 35▿
- J Med Chem 43: 843-58 (2000) 151
- Bioorg Med Chem Lett 16: 5561-6 (2006) 124
- Eur J Med Chem 127: 986-996 (2017) 75
- J Med Chem 60: 681-694 (2017) 74
- ACS Med Chem Lett 8: 835-840 (2017) 68
- Bioorg Med Chem Lett 16: 3975-80 (2006) 63
- J Med Chem 40: 3781-92 (1997) 59
- Eur J Med Chem 134: 218-229 (2017) 54
- Bioorg Med Chem 7: 2775-800 (1999) 50
- Bioorg Med Chem Lett 14: 1917-21 (2004) 49
- Bioorg Med Chem Lett 17: 4432-6 (2007) 47
- Bioorg Med Chem Lett 6: 1133-1138 (1996) 37
- Bioorg Med Chem Lett 9: 1481-6 (1999) 33
- Bioorg Med Chem Lett 6: 1099-1104 (1996) 32
- Bioorg Med Chem Lett 17: 4006-11 (2007) 29
- J Med Chem 35: 3803-12 (1992) 27
- J Med Chem 40: 3707-11 (1997) 24
- Bioorg Med Chem Lett 22: 2843-9 (2012) 23
- Bioorg Med Chem Lett 9: 2217-22 (1999) 21
- Bioorg Med Chem Lett 9: 2019-24 (1999) 21
- Bioorg Med Chem 4: 1401-10 (1996) 20
- J Med Chem 38: 898-905 (1995) 19
- J Med Chem 54: 4721-34 (2011) 17
- J Med Chem 34: 1222-5 (1991) 16
- ACS Chem Biol 4: 473-83 (2009) 14
- J Biol Chem 282: 36829-36 (2007) 14
- J Med Chem 50: 5886-9 (2007) 11
- J Med Chem 46: 1858-69 (2003) 9
- Bioorg Med Chem Lett 22: 4064-7 (2012) 9
- Bioorg Med Chem 15: 5519-28 (2007) 8
- ACS Med Chem Lett 4: 542-546 (2013) 6
- J Med Chem 40: 1941-6 (1997) 6
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- J Med Chem 61: 4456-4475 (2018) 2
- Bioorg Med Chem Lett 5: 315-318 (1995) 2
Institutions 16▿
- Parke-Davis Pharmaceutical Research 344
- Advinus Therapeutics 294
- Valeant Pharmaceuticals Research & Development 124
- Bristol-Myers Squibb Pharmaceutical Research Institute 78
- TBA 71
- Valeant Pharmaceutical Research And Development 63
- Bristol-Myers Squibb Research And Development 61
- Warner-Lambert 54
- University Of Wisconsin-Madison 43
- Pfizer 25
- Baylor College Of Medicine 23
- Gilead Sciences 13
- Yale University 9
- University Of Pennsylvania 9
- Sanofi Winthrop 6
- Ptc Therapeutics 2
Affinity: 0.030 to 1.5E+6 nM▿
- Ki 407
- IC50 746
- Kd 9
- EC50 57
- Affinity ≤ nM
Xtal structures: 19
Docked structures: 13
Catalog Cmpds: 38