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Found 201 with Last Name = 'pratt' and Initial = 'lm'
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121445((S)-2-Mercaptomethyl-hexanoic acid [(S)-5-amino-1-...)
Affinity DataKi:  19nMAssay Description:Compound was evaluated for inhibition of peptide deformylase, PDF.Fe of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121442(5-Guanidino-2-(2-mercaptomethyl-hexanoylamino)-pen...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for inhibition of peptide deformylase, PDF.Ni of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121444((R)-2-Butyl-N*1*-((S)-1-dimethylcarbamoyl-2,2-dime...)
Affinity DataIC50:  1nMAssay Description:Compound was evaluated for inhibition of peptide deformylase, PDF.Ni of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081851((2R,3R)-3-(cyclopentylmethyl)-2-((1-(dimethylamino...)
Affinity DataIC50:  2nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Coll-3 MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081851((2R,3R)-3-(cyclopentylmethyl)-2-((1-(dimethylamino...)
Affinity DataIC50:  2nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081869((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((4-meth...)
Affinity DataIC50:  3nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081866((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((4-meth...)
Affinity DataIC50:  3nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081860((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081871((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081872((2R,3R)-3-(cyclopentylmethyl)-2-{[(dimethylsulfamo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131303((S)-2-[(R)-2-Cyclohexylmethyl-3-(formyl-hydroxy-am...)
Affinity DataIC50:  6nMAssay Description:Inhibition against Escherichia coli peptide deformylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081865((2R,3R)-2-((1-(dimethylamino)-N-methylnaphthalene-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Gel-A MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131342((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  6nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081851((2R,3R)-3-(cyclopentylmethyl)-2-((1-(dimethylamino...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Strom-1 MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Inhibition against Escherichia coli peptide deformylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Compound was evaluated for inhibition of peptide deformylase, PDF.Ni of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Antibacterial activity of the compound against E. coli Peptide deformylase. NiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131290((S)-2-[(R)-2-Cyclopentylmethyl-3-(formyl-hydroxy-a...)
Affinity DataIC50:  8nMAssay Description:Inhibition against Escherichia coli peptide deformylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081851((2R,3R)-3-(cyclopentylmethyl)-2-((1-(dimethylamino...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Coll-3 MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Coll-3 MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081871((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50221045(CHEMBL3706628)
Affinity DataIC50:  9nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081862((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-4-oxo-4-(p...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131311(1-((S)-2-{(R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50:  10nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131324((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  10nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081869((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((4-meth...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131304((R)-2-[(Formyl-hydroxy-amino)-methyl]-heptanoic ac...)
Affinity DataIC50:  10nMAssay Description:Inhibition against Escherichia coli peptide deformylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131292((R)-2-[(Formyl-hydroxy-amino)-methyl]-4-methyl-pen...)
Affinity DataIC50:  10nMAssay Description:Inhibition against Escherichia coli peptide deformylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  10nMAssay Description:Antibacterial activity of the compound against E. coli Peptide deformylase. NiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081865((2R,3R)-2-((1-(dimethylamino)-N-methylnaphthalene-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081872((2R,3R)-3-(cyclopentylmethyl)-2-{[(dimethylsulfamo...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081862((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-4-oxo-4-(p...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081857((2R,3R)-3-(cyclopentylmethyl)-2-((N-cyclopropylmet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131315((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  10nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131343((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  10nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081866((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((4-meth...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131314((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  10nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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