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Found 951 with Last Name = 'rakhit' and Initial = 's'
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090516(5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090517(5-Isopropyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  0.290nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090519(CHEMBL300519 | [2-(5-Isopropyl-1H-indol-3-yl)-ethy...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386386(CHEMBL2046871)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090523(2-(5-tert-Butyl-1-methyl-1H-indol-3-yl)-ethylamine...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088870(CHEMBL171129 | Dimethyl-[2-(5-thiophen-3-yl-1H-ind...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088867(CHEMBL170192 | Dimethyl-[2-(5-thiophen-2-yl-1H-ind...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090522(5-Ethyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-...)
Affinity DataKi:  0.970nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088863(2-(5-Thiophen-2-yl-1H-indol-3-yl)-ethylamine | CHE...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088864(3-[2-((S)-2-Methoxymethyl-pyrrolidin-1-yl)-ethyl]-...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50176062(3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090521(5-tert-Butyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088869(3-[2-(2,5-Dimethyl-pyrrolidin-1-yl)-ethyl]-5-thiop...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088866(CHEMBL174355 | Dimethyl-{2-[5-(5-methyl-thiophen-2...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090515(5-Methyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088868(3-[2-(2,5-Dihydro-pyrrol-1-yl)-ethyl]-5-thiophen-2...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090518(5-Isopropyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole ...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386382(CHEMBL2046872)
Affinity DataKi:  5.41nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386379(CHEMBL2048416)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088860(CHEMBL422737 | {2-[5-(5-Chloro-thiophen-2-yl)-1H-i...)
Affinity DataKi:  7.60nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386380(CHEMBL2048417)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088865(CHEMBL174141 | {(S)-1-[2-(5-Thiophen-2-yl-1H-indol...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088864(3-[2-((S)-2-Methoxymethyl-pyrrolidin-1-yl)-ethyl]-...)
Affinity DataKi:  9.90nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090517(5-Isopropyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  11nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386388(CHEMBL2046877)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090519(CHEMBL300519 | [2-(5-Isopropyl-1H-indol-3-yl)-ethy...)
Affinity DataKi:  14nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090516(5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50049099(CHEMBL50492 | [2-(5-Ethyl-1H-indol-3-yl)-ethyl]-di...)
Affinity DataKi:  16nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088870(CHEMBL171129 | Dimethyl-[2-(5-thiophen-3-yl-1H-ind...)
Affinity DataKi:  17nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088861(3-(2-Pyrrolidin-1-yl-ethyl)-5-thiophen-2-yl-1H-ind...)
Affinity DataKi:  19nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088867(CHEMBL170192 | Dimethyl-[2-(5-thiophen-2-yl-1H-ind...)
Affinity DataKi:  23nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386385(CHEMBL2046876)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088862(5-(5-Chloro-thiophen-2-yl)-3-(2-pyrrolidin-1-yl-et...)
Affinity DataKi:  31nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088863(2-(5-Thiophen-2-yl-1H-indol-3-yl)-ethylamine | CHE...)
Affinity DataKi:  32nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  36nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386377(CHEMBL2046878)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090520(5-Ethyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole | CH...)
Affinity DataKi:  45nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090522(5-Ethyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-...)
Affinity DataKi:  47nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386378(CHEMBL2048415)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  48nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088869(3-[2-(2,5-Dimethyl-pyrrolidin-1-yl)-ethyl]-5-thiop...)
Affinity DataKi:  70nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088868(3-[2-(2,5-Dihydro-pyrrol-1-yl)-ethyl]-5-thiophen-2...)
Affinity DataKi:  107nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386383(CHEMBL2046873)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088865(CHEMBL174141 | {(S)-1-[2-(5-Thiophen-2-yl-1H-indol...)
Affinity DataKi:  113nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090515(5-Methyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H...)
Affinity DataKi:  118nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088866(CHEMBL174355 | Dimethyl-{2-[5-(5-methyl-thiophen-2...)
Affinity DataKi:  133nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386381(Nucynta | TAPENTADOL HYDROCHLORIDE | Tapentadol)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

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