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Found 224 with Last Name = 'ramjee' and Initial = 'm'
TargetCathepsin K(Homo sapiens (Human))
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134127(CHEMBL607122)
Affinity DataKi:  3.5nMAssay Description:Binding affinity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50161337(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-pyrrol...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50318879(CHEMBL607169 | N-((S)-1-((3aR,6aS)-4-benzoyl-6-oxo...)
Affinity DataKi:  10nMAssay Description:Binding affinity against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50161334(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-2-oxa-...)
Affinity DataKi:  40nMAssay Description:Binding affinity against human cathepsin KMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase B(Leishmania mexicana)
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134127(CHEMBL607122)
Affinity DataKi:  50nMAssay Description:Binding affinity against Leishmania mexicana cysteine peptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134127(CHEMBL607122)
Affinity DataKi:  93nMAssay Description:Binding affinity against cruzaineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50318879(CHEMBL607169 | N-((S)-1-((3aR,6aS)-4-benzoyl-6-oxo...)
Affinity DataKi:  173nMAssay Description:Binding affinity against cruzaineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134127(CHEMBL607122)
Affinity DataKi:  434nMAssay Description:Binding affinity against cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50161337(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-pyrrol...)
Affinity DataKi:  600nMAssay Description:Binding affinity against cruzaineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase B(Leishmania mexicana)
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50318879(CHEMBL607169 | N-((S)-1-((3aR,6aS)-4-benzoyl-6-oxo...)
Affinity DataKi:  691nMAssay Description:Binding affinity against Leishmania mexicana cysteine peptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase B(Leishmania mexicana)
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50161334(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-2-oxa-...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity against Leishmania mexicana cysteine peptidase B (CPB)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase B(Leishmania mexicana)
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50161337(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-pyrrol...)
Affinity DataKi:  1.17E+3nMAssay Description:Binding affinity against Leishmania mexicana cysteine peptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50161334(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-2-oxa-...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity against cruzaineMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50161337(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-pyrrol...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity against cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50161334(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-2-oxa-...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity against cathepsin SMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Amura Therapeutics

Curated by ChEMBL
LigandPNGBDBM50318879(CHEMBL607169 | N-((S)-1-((3aR,6aS)-4-benzoyl-6-oxo...)
Affinity DataKi: >4.50E+3nMAssay Description:Binding affinity against cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437403(CHEMBL2408771)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of porcine DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437403(CHEMBL2408771)
Affinity DataIC50:  0.270nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of wild type Abl1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437404(CHEMBL2408655)
Affinity DataIC50:  1nMAssay Description:Inhibition of porcine DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  1nMAssay Description:Inhibition of wild type Abl1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  1nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427747(CHEMBL2324926)
Affinity DataIC50:  1nMAssay Description:Inhibition of wild type Abl1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  1nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437403(CHEMBL2408771)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437404(CHEMBL2408655)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427750(CHEMBL2324923)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of wild type Abl1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  2nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427750(CHEMBL2324923)
Affinity DataIC50:  2nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  3nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease hepsin(Homo sapiens (Human))
University Of Helsinki

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427747(CHEMBL2324926)
Affinity DataIC50:  6nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437395(CHEMBL2408638)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  7nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427742(CHEMBL2324930)
Affinity DataIC50:  8nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437404(CHEMBL2408655)
Affinity DataIC50:  9nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437395(CHEMBL2408638)
Affinity DataIC50:  9nMAssay Description:Inhibition of porcine DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  10nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427750(CHEMBL2324923)
Affinity DataIC50:  11nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437404(CHEMBL2408655)
Affinity DataIC50:  11nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427745(CHEMBL2324927)
Affinity DataIC50:  12nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427747(CHEMBL2324926)
Affinity DataIC50:  12nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427750(CHEMBL2324923)
Affinity DataIC50:  12nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427741(CHEMBL2324931)
Affinity DataIC50:  13nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427744(CHEMBL2324928)
Affinity DataIC50:  14nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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