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Found 29 with Last Name = 'rasori' and Initial = 'r'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50064858((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...)
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092632(8-(3-Nitro-phenyl)-6-pyridin-4-ylmethyl-quinoline ...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092630(8-(3-Azido-phenyl)-6-pyridin-4-ylmethyl-quinoline ...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092626(8-(3-Azido-phenyl)-6-(4-iodo-imidazol-1-ylmethyl)-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092623(3-Benzyl-5-phenyl-3,5-dihydro-1,3,5,6-tetraaza-cyc...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092633(8-(3-Azido-phenyl)-6-iodo-quinoline | CHEMBL127994)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092627(8-(5-Azido-2-iodo-phenyl)-6-pyridin-4-ylmethyl-qui...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092624(6-Imidazol-1-ylmethyl-8-phenyl-quinoline | CHEMBL4...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092629(CHEMBL123576 | [8-(3-Iodo-phenyl)-quinolin-6-yl]-p...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074976(2-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...)
Affinity DataIC50:  25nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092628(6-Azido-8-(3-iodo-phenyl)-quinoline | CHEMBL124575)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092631(4-(3-Cyclopentyloxy-4-methoxy-phenyl)-1-[3-iodo-5-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074972(2,5-Bis-(3-cyclopentyloxy-4-methoxy-phenyl)-furan ...)
Affinity DataIC50:  44nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074965(4-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...)
Affinity DataIC50:  65nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074974(1-[2,5-Bis-(3,4-dimethoxy-phenyl)-furan-3-yl]-etha...)
Affinity DataIC50:  120nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074968(2-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...)
Affinity DataIC50:  190nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092625(3-[3-Iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)-b...)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074977((2,5-Diphenyl-furan-3-yl)-phenyl-methanone | CHEMB...)
Affinity DataIC50:  340nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074969(3-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...)
Affinity DataIC50:  370nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074967(2,5-Bis-(3,4-dimethoxy-phenyl)-furan | CHEMBL11093...)
Affinity DataIC50:  560nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074975(CHEMBL325846 | [2-(3-Cyclopentyloxy-4-methoxy-phen...)
Affinity DataIC50:  590nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074973(2-[3-Benzenesulfonyl-5-(3-cyclopentyloxy-4-methoxy...)
Affinity DataIC50:  740nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074970(2-[4-Benzenesulfonyl-5-(3-cyclopentyloxy-4-methoxy...)
Affinity DataIC50:  770nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074966(4-(2,5-Diphenyl-furan-3-yl)-morpholine | CHEMBL323...)
Affinity DataIC50:  2.30E+3nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)
Affinity DataIC50:  4.00E+3nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074971(4-[(R)-2-(4-Cyclopentyloxy-3-methoxy-phenyl)-2-phe...)
Affinity DataIC50:  5.00E+3nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50064858((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074964(2,5-diphenylfuran | CHEMBL109224 | PPF)
Affinity DataIC50: >1.00E+4nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed