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Found 106 with Last Name = 'rebello' and Initial = 's'
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123781(4-(4-Amino-quinazolin-7-ylmethyl)-1-(6-chloro-benz...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity (in vitro) of the compound towards human Coagulation factor X was determined at 10 mg/kg peroral doseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12596(4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity (in vitro) of the compound towards human Coagulation factor X was determined at 5 mg/kg peroral doseMore data for this Ligand-Target Pair
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156461(3-[4-(5-Aminomethyl-2-fluoro-phenyl)-piperidine-1-...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156460(3-[4-(3-Aminomethyl-phenyl)-piperidine-1-carbonyl]...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12595(4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-1-{[1-(2-...)
Affinity DataKi:  3nMAssay Description:Binding affinity (in vitro) of the compound towards human Coagulation factor X was determined at 10 mg/kg peroral doseMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123766(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1-met...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123788(4-(6-Bromo-benzo[b]thiophene-2-sulfonyl)-1-(1H-pyr...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123767(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-py...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123782(4-(6-Chloro-thieno[2,3-b]pyridine-2-sulfonyl)-1-(1...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156457(CHEMBL186730 | [4-(5-Aminomethyl-2-fluoro-phenyl)-...)
Affinity DataKi:  4.30nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123778(2-{2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-...)
Affinity DataKi:  8nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123765(CHEMBL158689 | {2-[4-(6-Chloro-benzo[b]thiophene-2...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123789(4-(5'-Chloro-[2,2']bithiophenyl-5-sulfonyl)-1-(1H-...)
Affinity DataKi:  23nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167517(CHEMBL191546 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  32nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123785(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(5-oxy...)
Affinity DataKi:  38nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167534(CHEMBL370284 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  41nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167531(CHEMBL365527 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  41nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123770(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-py...)
Affinity DataKi:  45nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123775(4-[2-(4-Chloro-phenyl)-ethenesulfonyl]-1-(1H-pyrro...)
Affinity DataKi:  48nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167524(CHEMBL192963 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  49nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167525(CHEMBL193514 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  57nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156459(3-[4-(5-Aminomethyl-2-fluoro-phenyl)-piperidine-1-...)
Affinity DataKi:  59nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167530(CHEMBL189101 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  61nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167514(CHEMBL370463 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  68nMAssay Description:Binding affinity of compound towards Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50156458(3-[4-(5-Aminomethyl-2-fluoro-phenyl)-piperidine-1-...)
Affinity DataKi:  88nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167520(CHEMBL365148 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  101nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167526(CHEMBL365189 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  116nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167522(CHEMBL372028 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  124nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167521(CHEMBL364661 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  125nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167511(CHEMBL189531 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  128nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123774(4-[2-(5-Chloro-thiophen-2-yl)-ethanesulfonyl]-1-(1...)
Affinity DataKi:  128nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  140nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167523(CHEMBL190103 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  141nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123776(CHEMBL161158 | {2-[4-(6-Chloro-benzo[b]thiophene-2...)
Affinity DataKi:  154nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167535(CHEMBL191007 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  155nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167533(CHEMBL435694 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  162nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167510(CHEMBL361040 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  185nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167529(CHEMBL372912 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  197nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167515(1-{3-[4-(3-Aminomethyl-phenyl)-piperidine-1-carbon...)
Affinity DataKi:  240nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167513(CHEMBL192214 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  246nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167528(CHEMBL436537 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  290nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167519(CHEMBL190135 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  310nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167527(CHEMBL189983 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  368nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167518(CHEMBL189372 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  373nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167516(CHEMBL191731 | [4-(3-Aminomethyl-phenyl)-piperidin...)
Affinity DataKi:  497nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123773(4-(Benzo[b]thiophene-2-sulfonyl)-1-(1H-pyrrolo[3,2...)
Affinity DataKi:  959nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123780(1-(4-Amino-1H-pyrrolo[3,2-c]pyridin-2-ylmethyl)-4-...)
Affinity DataKi:  1.02E+3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123779(4-(6-Chloro-thieno[3,2-b]pyridine-2-sulfonyl)-1-(1...)
Affinity DataKi:  1.20E+3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123784(4-(3-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-py...)
Affinity DataKi: >1.20E+3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123777(4-[2-(5-Chloro-4-methoxy-thiophen-2-yl)-ethenesulf...)
Affinity DataKi: >1.20E+3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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