Affinity DataKi: 0.200nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.219nMAssay Description:Displacement of [3H]paraiodoclonidine from imidazoline I1 receptor in rat PC12 cells after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nM ΔG°: -57.3kJ/molepH: 7.35 T: 2°CAssay Description:Binding assays were performed at 37° C. using [125I]LNP 911 as radioligand following the general procedure described but adapted to washed whole ...More data for this Ligand-Target Pair
Affinity DataKi: 0.221nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.274nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.535nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Affinity DataKi: 0.780nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Affinity DataKi: 0.850nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Affinity DataKi: 0.910nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.933nMAssay Description:Displacement of [3H]paraiodoclonidine from imidazoline I1 receptor in rat PC12 cells after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to emopamil binding proteinMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nM ΔG°: -50.8kJ/molepH: 7.35 T: 2°CAssay Description:Binding assays were performed at 37° C. using [125I]LNP 911 as radioligand following the general procedure described but adapted to washed whole ...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nM ΔG°: -50.8kJ/molepH: 7.35 T: 2°CAssay Description:Binding assays were performed at 37° C. using [125I]LNP 911 as radioligand following the general procedure described but adapted to washed whole ...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]RX821002 from human alpha2 adrenoceptor expressed in CHO cell membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Binding affinity to human tryptase beta2More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Binding affinity to rat tryptaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of fluorescent-tagged R1881 from androgen receptor after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 8.10nM ΔG°: -48.0kJ/molepH: 7.35 T: 2°CAssay Description:Binding assays were performed at 37° C. using [125I]LNP 911 as radioligand following the general procedure described but adapted to washed whole ...More data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]RX821001 from human alpha2A adrenoceptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]RX821001 from human alpha2C adrenoceptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of fluorescent-tagged R1881 from androgen receptor after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]paraiodoclonidine from imidazoline I1 receptor in rat PC12 cells after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]RX821001 from human alpha2C adrenoceptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 19nM ΔG°: -45.8kJ/molepH: 7.35 T: 2°CAssay Description:Binding assays were performed at 37° C. using [125I]LNP 911 as radioligand following the general procedure described but adapted to washed whole ...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma countingMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Leiden University
Curated by PDSP Ki Database
Leiden University
Curated by PDSP Ki Database
Affinity DataKi: 26nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair