Affinity DataKi: 0.0400nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0440nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Actelion Pharmaceuticals
Curated by ChEMBL
Actelion Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Antagonist activity at orexin-1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.0710nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0890nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0940nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0980nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:Antagonist activity at orexin-2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Affinity DataKi: 0.470nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre For Therapeutic Research
Curated by PDSP Ki Database
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair