TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of FAS thioster domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of FAS thioster domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of FAS thioster domain (unknown origin)More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 180nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 210nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 230nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 280nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 300nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 370nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 400nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 450nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 520nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 680nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 790nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 1.02E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 1.04E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human FAS thioster domain preincubated for 30 mins followed by 4-methylumbelliferyl heptanoate substrate addition measured every 5 mins...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 1.35E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 1.35E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human FAS thioster domain preincubated for 30 mins followed by 4-methylumbelliferyl heptanoate substrate addition measured every 5 mins...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 1.72E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of caspase-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Z-Leu-Leu-Glu-AMC substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of human FAS thioster domain preincubated for 30 mins followed by 4-methylumbelliferyl heptanoate substrate addition measured every 5 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of caspase-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Z-Leu-Leu-Glu-AMC substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DNA polymerase-gamma (unknown origin) assessed as incorporation of Br(d)UTP by colorimetric analysisMore data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of caspase-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Z-Leu-Leu-Glu-AMC substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of human FAS thioster domain preincubated for 30 mins followed by 4-methylumbelliferyl heptanoate substrate addition measured every 5 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of human FAS thioster domain preincubated for 30 mins followed by 4-methylumbelliferyl heptanoate substrate addition measured every 5 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of caspase-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Z-Leu-Leu-Glu-AMC substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of caspase-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Z-Leu-Leu-Glu-AMC substrate additio...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 3.67E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair