Affinity DataKi: 1.50E+3nMAssay Description:Binding affinity to wild type human COX2 expressed in insect cells using [1-14C]-arachidonic acid as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Binding affinity to wild type human COX2 expressed in insect cells using [1-14C]-arachidonic acid as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type ovine COX1 expressed in ram seminal vesicles using [1-14C]-arachidonic acid as substrate incubated for 17 mins at 25 degC fol...More data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Inhibition of wild type mouse COX2 expressed in insect cells using [1-14C]-arachidonic acid as substrate incubated for 17 mins at 25 degC followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of COX2 in human HNSCC1483 cells using [1-14C]-arachidonic acid as substrate assessed as inhibition of substrate oxygenation preincubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of wild type human COX2 expressed in insect cells using [1-14C]-arachidonic acid as substrate incubated for 17 mins at 25 degC followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 267nMAssay Description:Inhibition of wild type mouse COX2 expressed in insect cells using [1-14C]-arachidonic acid as substrate incubated for 17 mins at 25 degC followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 388nMAssay Description:Inhibition of wild type human COX2 expressed in insect cells using [1-14C]-arachidonic acid as substrate incubated for 17 mins at 25 degC followed by...More data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of wild type ovine COX1 expressed in ram seminal vesicles using [1-14C]-arachidonic acid as substrate incubated for 17 mins at 25 degC fol...More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Tested for the 50% inhibition level against [125I]- gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 2.00E+5nMAssay Description:Tested for the 50% inhibition level against [125I]- gastrin binding in AR42J cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKd: 3.20nMAssay Description:Tested in vitro for gastrin binding to gastrin receptors from guinea pig gastric glandsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKd: 1.40nMAssay Description:Tested in vitro by the gastrin binding assay for the competitive binding with iodinated gastrin for the gastrin receptors in AR42J cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Tested for the 50% inhibition level against [125I]- gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Tested for the 50% inhibition level against [125I]- gastrin binding in AR42J cellsMore data for this Ligand-Target Pair