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Found 54 with Last Name = 'rozamus' and Initial = 'lw'
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36608(Rapamycin C-7, analog 1)
Affinity DataKi:  0.600nM EC50:  1nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataKi:  1nM EC50:  30nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36627(Rapamycin C-7, analog 16a)
Affinity DataKi:  1nM EC50:  45nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36623(Rapamycin C-7, analog 12)
Affinity DataKi:  1nM EC50:  2nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36612(Rapamycin C-7, analog 6a)
Affinity DataKi:  1nM EC50:  4nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36613(Rapamycin C-7, analog 6b)
Affinity DataKi:  1nM EC50:  4nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36622(Rapamycin C-7, analog 11b)
Affinity DataKi:  1.5nM EC50:  70nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36619(Rapamycin C-7, analog 10a)
Affinity DataKi:  3nM EC50:  20nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36610(Rapamycin C-7, analog 5a)
Affinity DataKi:  3.5nM EC50:  10nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36615(Rapamycin C-7, analog 7b)
Affinity DataKi:  3.70nM EC50:  2.50E+3nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36611(Rapamycin C-7, analog 5b)
Affinity DataKi:  4nM EC50:  200nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36614(Rapamycin C-7, analog 7a)
Affinity DataKi:  4.5nM EC50: >1.00E+4nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36625(Rapamycin C-7, analog 14a)
Affinity DataKi:  5nM EC50:  6nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36620(Rapamycin C-7, analog 10b)
Affinity DataKi:  6nM EC50:  20nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36618(Rapamycin C-7, analog 9)
Affinity DataKi:  7nM EC50: >1.00E+3nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36626(Rapamycin C-7, analog 15a)
Affinity DataKi:  7nM EC50:  50nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36616(Rapamycin C-7, analog 8a)
Affinity DataKi:  9nM EC50:  1.00E+3nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36621(Rapamycin C-7, analog 11a)
Affinity DataKi:  10nM EC50:  11nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36624(Rapamycin C-7, analog 13)
Affinity DataKi:  29nM EC50:  300nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36628(Rapamycin C-7, analog 17a)
Affinity DataKi:  30nM EC50:  90nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36617(Rapamycin C-7, analog 8b)
Affinity DataKi:  38nM EC50: >1.00E+3nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086083(1-[2-(3,4,5-Trimethoxy-phenyl)-pent-4-enoyl]-piper...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086090(1-[2-(3,4,5-Trimethoxy-phenyl)-butyryl]-piperidine...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086094(1-[2-(3,4,5-Trimethoxy-phenyl)-pentanoyl]-piperidi...)
Affinity DataIC50:  3.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086077(1-[3-Cyclopropyl-2-(3,4,5-trimethoxy-phenyl)-propi...)
Affinity DataIC50:  4.40nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132554((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086092(1-[3-Methyl-2-(3,4,5-trimethoxy-phenyl)-butyryl]-p...)
Affinity DataIC50:  5.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132541((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132541((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132550((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-propionyl]-...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086078(1-(2-Cyclohexyl-2-phenyl-acetyl)-piperidine-2-carb...)
Affinity DataIC50:  12nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132558((E)-(12S,13R,14S,17R,21S,23S,24R,25R,27R)-17-Ethyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132542((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)
Affinity DataIC50:  15nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086082(1-[2-(3,4,5-Trimethoxy-phenyl)-pent-4-enoyl]-piper...)
Affinity DataIC50:  19nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086087(1-(3-Methyl-2-phenyl-butyryl)-piperidine-2-carboxy...)
Affinity DataIC50:  19nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132560((S)-1-((S)-2-Benzo[1,3]dioxol-5-yl-butyryl)-piperi...)
Affinity DataIC50:  26nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086085(1-(2-Phenyl-butyryl)-piperidine-2-carboxylic acid ...)
Affinity DataIC50:  40nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132544((S)-1-((S)-2-Phenyl-butyryl)-piperidine-2-carboxyl...)
Affinity DataIC50:  40nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132544((S)-1-((S)-2-Phenyl-butyryl)-piperidine-2-carboxyl...)
Affinity DataIC50:  40nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086075(1-[2-(3,4,5-Trimethoxy-phenyl)-pentanoyl]-piperidi...)
Affinity DataIC50:  43nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50132551(1-(1-Ethyl-propylcarbamoyl)-piperidine-2-carboxyli...)
Affinity DataIC50:  64nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086086(1-[3-Methyl-2-(3,4,5-trimethoxy-phenyl)-butyryl]-p...)
Affinity DataIC50:  65nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086079(1-(2-Cyclohexyl-2-phenyl-acetyl)-piperidine-2-carb...)
Affinity DataIC50:  66nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086080(1-(2-Phenyl-propionyl)-piperidine-2-carboxylic aci...)
Affinity DataIC50:  94nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086089(1-[3-Cyclopropyl-2-(3,4,5-trimethoxy-phenyl)-propi...)
Affinity DataIC50:  126nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086084(1-(2-Phenyl-butyryl)-piperidine-2-carboxylic acid ...)
Affinity DataIC50:  133nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086081(1-(3-Methyl-2-phenyl-butyryl)-piperidine-2-carboxy...)
Affinity DataIC50:  150nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086093(1-[2-(3,4,5-Trimethoxy-phenyl)-butyryl]-piperidine...)
Affinity DataIC50:  187nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM50086076(1-Diphenylacetyl-piperidine-2-carboxylic acid 1-(3...)
Affinity DataIC50:  273nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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