Compile Data Set for Download or QSAR
maximum 50k data
Found 92 with Last Name = 'ruhter' and Initial = 'g'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100358((S)-3-[(3-Pyridin-4-yl-3-aza-spiro[5.5]undecane-9-...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100346((S)-2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-3-[...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration of the compound against alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50092126(2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-3-[(3-p...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50092105((S)-2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-5-o...)
Affinity DataIC50:  2nMAssay Description:Inhibition of binding of fibrinogen to purified human GPIIb-IIIa in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100350((S)-5-Oxo-5-(9-pyridin-4-yl-3,9-diaza-spiro[5.5]un...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration of the compound against alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111398((S)-2-(Isoxazole-4-sulfonylamino)-5-oxo-5-(2-pyrid...)
Affinity DataIC50:  2nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100365((S)-2-Benzyloxycarbonylamino-3-[(3-pyridin-4-yl-3-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100360((S)-2-(Butane-1-sulfonylamino)-3-[(3-pyridin-4-yl-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100344((S)-2-Butoxycarbonylamino-5-oxo-5-(9-pyridin-4-yl-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of binding of fibrinogen to purified human GPIIb-IIIa in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111419(3-Oxo-3-[4-(2-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50:  4nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100351((S)-2-Benzyloxycarbonylamino-5-oxo-5-(9-pyridin-4-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of binding of fibrinogen to purified human GPIIb-IIIa in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100376((S)-2-Butoxycarbonylamino-3-[(3-pyridin-4-yl-3-aza...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111424((S)-2-Butoxycarbonylamino-5-oxo-5-(2-pyridin-4-yl-...)
Affinity DataIC50:  17nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111404(3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50:  17nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100347((S)-2-(Butane-1-sulfonylamino)-5-oxo-5-(9-pyridin-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of binding of fibrinogen to purified human GPIIb-IIIa in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111432(CHEMBL12581 | [2-Oxo-4-(8-pyridin-4-yl-2,8-diaza-s...)
Affinity DataIC50:  25nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111401((S)-2-Benzyloxycarbonylamino-5-oxo-5-(2-pyridin-4-...)
Affinity DataIC50:  25nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111418(3-Oxo-3-[4-(2-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50:  25nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111428(7-Oxo-7-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec-2-...)
Affinity DataIC50:  43nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100352(3-Oxo-3-[4-(9-pyridin-4-yl-3,9-diaza-spiro[5.5]und...)
Affinity DataIC50:  43nMAssay Description:Inhibitory concentration of the compound against alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111421(CHEMBL417800 | [5-(2-Pyridin-4-yl-2,8-diaza-spiro[...)
Affinity DataIC50:  47nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100363(3-{[3-(4-Carbamimidoyl-phenyl)-3-aza-spiro[5.5]und...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111405(3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50:  87nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111399(CHEMBL275769 | [4-(2-Pyridin-4-yl-2,8-diaza-spiro[...)
Affinity DataIC50:  90nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111415(CHEMBL275967 | [1-(2-Pyridin-4-yl-2,8-diaza-spiro[...)
Affinity DataIC50:  106nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111427(3-Oxo-3-[4-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50:  113nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111429(CHEMBL12878 | [1-(2-Pyridin-4-yl-2,8-diaza-spiro[4...)
Affinity DataIC50:  115nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111412(3-Oxo-3-[4-(2-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50:  136nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111423(CHEMBL12631 | [1-(2-Pyridin-4-yl-2,8-diaza-spiro[4...)
Affinity DataIC50:  138nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111411(CHEMBL13008 | [1-(8-Pyridin-4-yl-2,8-diaza-spiro[4...)
Affinity DataIC50:  153nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100369((3-Pyridin-4-yl-3-aza-spiro[5.5]undec-9-ylamino)-a...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100356(3-[9-(4-Carbamimidoyl-phenyl)-3,9-diaza-spiro[5.5]...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration of the compound against alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111409(8-Oxo-8-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec-2-...)
Affinity DataIC50:  196nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100343(2-{1-[9-(4-pyridyl)-3,9-diazaspiro[5.5]undec-3-ylc...)
Affinity DataIC50:  210nMAssay Description:Inhibition of binding of fibrinogen to purified human GPIIb-IIIa in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111414(3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50:  225nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111407(3-[2-Oxo-4-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Affinity DataIC50:  238nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100353(5-Oxo-5-(9-pyridin-4-yl-3,9-diaza-spiro[5.5]undec-...)
Affinity DataIC50:  240nMAssay Description:Inhibitory concentration of the compound against alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100362(CHEMBL24671 | [9-(4-Cyclohexyl-piperidine-1-carbon...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100372((3-Pyridin-4-yl-3-aza-spiro[5.5]undec-9-yloxy)-ace...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111403(CHEMBL13177 | [4-(2-Pyridin-4-yl-2,8-diaza-spiro[4...)
Affinity DataIC50:  252nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111400(3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...)
Affinity DataIC50:  254nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100355(6-Oxo-6-(9-pyridin-4-yl-3,9-diaza-spiro[5.5]undec-...)
Affinity DataIC50:  260nMAssay Description:Inhibitory concentration of the compound against alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100342(7-Oxo-7-(9-pyridin-4-yl-3,9-diaza-spiro[5.5]undec-...)
Affinity DataIC50:  270nMAssay Description:Inhibition of binding of fibrinogen to purified human GPIIb-IIIa in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100373(4-[(3-Pyridin-4-yl-3-aza-spiro[5.5]undecane-9-carb...)
Affinity DataIC50:  319nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111431(CHEMBL274835 | [4-(2-Pyridin-4-yl-2,8-diaza-spiro[...)
Affinity DataIC50:  320nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100370(3-Methyl-4-[(3-pyridin-4-yl-3-aza-spiro[5.5]undeca...)
Affinity DataIC50:  332nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100374(CHEMBL280622 | [9-(4-Pyridin-4-yl-piperazine-1-car...)
Affinity DataIC50:  364nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111425(CHEMBL273482 | N-[1-(2-Pyridin-4-yl-2,8-diaza-spir...)
Affinity DataIC50:  447nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50100368((S)-3-[(3-Pyridin-4-yl-3-aza-spiro[5.5]undecane-9-...)
Affinity DataIC50:  616nMAssay Description:In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50111406(CHEMBL12877 | [4-(2-Pyridin-4-yl-2,8-diaza-spiro[4...)
Affinity DataIC50:  688nMAssay Description:In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 92 total ) | Next | Last >>
Jump to: