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Found 424 with Last Name = 'rybczynski' and Initial = 'p'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108418(US8604206, 13 | US8604206, 14)
Affinity DataKi:  0.900nM IC50:  17.1nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108417(US8604206, 6)
Affinity DataKi:  3.06nM IC50:  5.80nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108418(US8604206, 13 | US8604206, 14)
Affinity DataKi:  4nM IC50:  7nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)
Affinity DataKi:  4nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108423(US8604206, (3R,4R,5R)-5((S)-hydroxy(phenyl)methyl)...)
Affinity DataKi:  8.90nM IC50:  17nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153302(3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[2-hydroxy...)
Affinity DataKi:  9nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108419(US8604206, 10 | US8604206, 9)
Affinity DataKi:  10nM IC50:  20nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153298(3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[4-ethyl-2...)
Affinity DataKi:  10nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153301(3-(4-Ethoxy-phenyl)-1-[2-hydroxy-4-methyl-6-(3,4,5...)
Affinity DataKi:  10nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153312(1-[2-Hydroxy-4-methyl-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  10nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153305(1-[4-Ethyl-2-hydroxy-6-(3,4,5-trihydroxy-6-hydroxy...)
Affinity DataKi:  10nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108417(US8604206, 6)
Affinity DataKi:  13.6nM IC50:  25.9nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108424(US8604206, (3R,4R,5S)-5(2-hydroxypropan-2-yl)piper...)
Affinity DataKi:  15nM IC50:  29nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108418(US8604206, 13 | US8604206, 14)
Affinity DataKi:  16nM IC50:  38nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153293(1-[4-Chloro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  20nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153309(3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[2-hydroxy...)
Affinity DataKi:  20nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153296(1-[4-Chloro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  30nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153294(3-(4-Ethoxy-phenyl)-1-[4-ethyl-2-hydroxy-6-(3,4,5-...)
Affinity DataKi:  30nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM47182(US8604206, (3R,4R,5S)-5-((R)-1-fluoropropyl)-piper...)
Affinity DataKi:  31nM IC50:  60nMAssay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108419(US8604206, 10 | US8604206, 9)
Affinity DataKi:  35nM IC50:  66nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153313(3-Cyclohexyl-1-[2-hydroxy-4-methyl-6-(3,4,5-trihyd...)
Affinity DataKi:  40nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108419(US8604206, 10 | US8604206, 9)
Affinity DataKi:  44nM IC50:  107nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108418(US8604206, 13 | US8604206, 14)
Affinity DataKi:  49.8nM IC50:  94.6nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)
Affinity DataKi:  50nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108422(US8604206, (3R,4R,5S)-5-benzyl-piperidine-3,4-diol)
Affinity DataKi:  67nM IC50:  127nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153292(1-[4-Fluoro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  70nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153306(1-[2-Hydroxy-4-methyl-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  70nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153299(1-[4-Chloro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  80nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108424(US8604206, (3R,4R,5S)-5(2-hydroxypropan-2-yl)piper...)
Affinity DataKi:  97nM IC50:  234nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153304(3-(4-Ethoxy-phenyl)-1-[2-hydroxy-4-isopropyl-6-(3,...)
Affinity DataKi:  110nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM47182(US8604206, (3R,4R,5S)-5-((R)-1-fluoropropyl)-piper...)
Affinity DataKi:  121nM IC50:  291nMAssay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108419(US8604206, 10 | US8604206, 9)
Affinity DataKi:  142nM IC50:  343nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153307(1-[2-Hydroxy-4-isopropyl-6-(3,4,5-trihydroxy-6-hyd...)
Affinity DataKi:  150nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153303(3-Furan-3-yl-1-[2-hydroxy-4-methyl-6-(3,4,5-trihyd...)
Affinity DataKi:  230nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108422(US8604206, (3R,4R,5S)-5-benzyl-piperidine-3,4-diol)
Affinity DataKi:  273nM IC50:  659nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153311(1-[2-Amino-4-methyl-6-(3,4,5-trihydroxy-6-hydroxym...)
Affinity DataKi:  290nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Homo sapiens (Human))
Amicus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50358321(CHEMBL1922579 | CHEMBL1922581)
Affinity DataKi:  300nMAssay Description:Inhibition of human beta galactosidaseMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153308(1-[2-Amino-4-methyl-6-(3,4,5-trihydroxy-6-hydroxym...)
Affinity DataKi:  520nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153313(3-Cyclohexyl-1-[2-hydroxy-4-methyl-6-(3,4,5-trihyd...)
Affinity DataKi:  1.08E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153297(1-[2-Amino-4-methyl-6-(3,4,5-trihydroxy-6-hydroxym...)
Affinity DataKi:  1.28E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153312(1-[2-Hydroxy-4-methyl-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  1.32E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108423(US8604206, (3R,4R,5R)-5((S)-hydroxy(phenyl)methyl)...)
Affinity DataKi:  1.36E+3nM IC50:  3.29E+3nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153306(1-[2-Hydroxy-4-methyl-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  1.38E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153302(3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[2-hydroxy...)
Affinity DataKi:  1.46E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153301(3-(4-Ethoxy-phenyl)-1-[2-hydroxy-4-methyl-6-(3,4,5...)
Affinity DataKi:  1.57E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153300(1-[2-Chloro-6-(3,4,5-trihydroxy-6-hydroxymethyl-te...)
Affinity DataKi: >1.70E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153310(1-[2-Chloro-6-(3,4,5-trihydroxy-6-hydroxymethyl-te...)
Affinity DataKi: >1.70E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153295(1-[2-Chloro-6-(3,4,5-trihydroxy-6-hydroxymethyl-te...)
Affinity DataKi: >1.70E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153292(1-[4-Fluoro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  3.69E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50153293(1-[4-Chloro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...)
Affinity DataKi:  3.75E+3nMAssay Description:In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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