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Found 288 with Last Name = 'salar' and Initial = 'u'
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237977(CHEMBL3310952)
Affinity DataKi:  820nMAssay Description:Competitive inhibition of bovine xanthine oxidase using varying levels of xanthine as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222435(N'',N'''-Bis[(E)-(2,6-dichlorophenyl)methylide...)
Affinity DataKi:  1.78E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222429(N'',N'''-Bis[(E)-(2-nitrophenyl)methylidene]ca...)
Affinity DataKi:  1.81E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222428(N'',N'''-Bis[(E)-(4-nitrophenyl)methylidene]ca...)
Affinity DataKi:  2.35E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222431(N'',N'''-Bis[(E)-(4-bromophenyl)methylidene]ca...)
Affinity DataKi:  2.52E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222430(N'',N'''-Bis[(E)-(2-chloro-5-nitrophenyl)methy...)
Affinity DataKi:  3.58E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222433(N'',N'''-Bis[(E)-(2-chlorophenyl)methylidene]c...)
Affinity DataKi:  4.12E+3nMpH: 7.4Assay Description:Kinetic studies were performed by using different concentration of inhibitors over different concentrations of substrate (4-NPA) such as 0.175, 0.35,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237969(CHEMBL4059808)
Affinity DataKi:  7.27E+3nMAssay Description:Competitive inhibition of bovine xanthine oxidase using varying levels of xanthine as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237973(CHEMBL200555)
Affinity DataKi:  1.50E+4nMAssay Description:Competitive inhibition of bovine xanthine oxidase using varying levels of xanthine as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237975(CHEMBL4098314)
Affinity DataKi:  1.55E+4nMAssay Description:Competitive inhibition of bovine xanthine oxidase using varying levels of xanthine as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237974(CHEMBL4081809)
Affinity DataKi:  5.13E+4nMAssay Description:Agonistic activity measures the ability to induce alkaline phosphatase in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193719(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(2-fluoro...)
Affinity DataIC50:  100nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193733(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3,4-dich...)
Affinity DataIC50:  120nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193734(2-(4-(di(1H-indol-3-yl)methyl)benzoyl)-N-(4(triflu...)
Affinity DataIC50:  200nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193720(N-(2-Chlorophenyl)-2-(4-(di(1H-indol-3-yl)methyl)b...)
Affinity DataIC50:  500nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237925(CHEMBL4103223)
Affinity DataIC50:  580nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237961(CHEMBL4060753)
Affinity DataIC50:  850nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237964(CHEMBL4090465)
Affinity DataIC50:  920nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237931(CHEMBL4095459)
Affinity DataIC50:  920nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237975(CHEMBL4098314)
Affinity DataIC50:  960nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate preincubated for 10 mins followed by substrate addition measured for 15 mins by spe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237942(CHEMBL4078955)
Affinity DataIC50:  1.07E+3nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 44-53 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237915(CHEMBL4069435)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237939(CHEMBL4077330)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50233861(CHEMBL4084524)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237962(CHEMBL4079164)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237946(CHEMBL4105082)
Affinity DataIC50:  1.33E+3nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237915(CHEMBL4069435)
Affinity DataIC50:  1.33E+3nMAssay Description:Effect on functional cellular GR-antagonism (GRAF) in human Glucocorticoid receptor (GR) expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237920(CHEMBL4087225)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222428(N'',N'''-Bis[(E)-(4-nitrophenyl)methylidene]ca...)
Affinity DataIC50:  1.33E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222430(N'',N'''-Bis[(E)-(2-chloro-5-nitrophenyl)methy...)
Affinity DataIC50:  1.37E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237965(CHEMBL4068298)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222435(N'',N'''-Bis[(E)-(2,6-dichlorophenyl)methylide...)
Affinity DataIC50:  1.46E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237928(CHEMBL4084312)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237916(CHEMBL4094534)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM222429(N'',N'''-Bis[(E)-(2-nitrophenyl)methylidene]ca...)
Affinity DataIC50:  1.85E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
University of Karachi

LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)
Affinity DataIC50:  1.86E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237923(CHEMBL4075025)
Affinity DataIC50:  1.94E+3nMAssay Description:Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237963(CHEMBL4098180)
Affinity DataIC50:  1.99E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50140241(Allopurinol | Aloral | Aluline 100 | Aluline 300 |...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate preincubated for 10 mins followed by substrate addition measured for 15 mins by spe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable maltase-glucoamylase 2(Homo sapiens)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable maltase-glucoamylase 2(Homo sapiens)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50528910(CHEMBL4472850)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50233856(CHEMBL4092265)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237922(CHEMBL4103420)
Affinity DataIC50:  2.13E+3nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 3-4 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50092444(CHEMBL3586121)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50160569(CHEMBL3785671)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237937(CHEMBL1372043)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable maltase-glucoamylase 2(Homo sapiens)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50528909(CHEMBL4449615)
Affinity DataIC50:  2.21E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237926(CHEMBL4080152)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193729(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3-fluoro...)
Affinity DataIC50:  2.30E+3nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50237918(CHEMBL4093867)
Affinity DataIC50:  2.31E+3nMAssay Description:Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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