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Found 555 with Last Name = 'santos' and Initial = 'o'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306472(6-fluoro-3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306469(6-fluoro-3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306480(3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  1.33nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306477(6-fluoro-3-(1-(2-(7-methoxybenzofuran-3-yl)propyl)...)
Affinity DataKi:  1.97nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306479(3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  2.55nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306471(3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Affinity DataKi:  2.85nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306488(3-(1-(2-(5-chlorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306460(3-(1-(2-(5-fluorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  3.14nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306473(5-fluoro-3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  3.17nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306474(3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Affinity DataKi:  3.24nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306467(3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Affinity DataKi:  3.36nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306470(3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Affinity DataKi:  3.36nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306485(3-(1-(2-(6-chlorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  3.54nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306468(5-fluoro-3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  3.63nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306475(3-(1-(2-(7-methoxybenzofuran-3-yl)propyl)-1,2,3,6-...)
Affinity DataKi:  3.98nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306461(3-(1-(2-(5-fluorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  4.13nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306474(3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Affinity DataKi:  5.14nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306465(6-fluoro-3-(1-(2-(5-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306471(3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Affinity DataKi:  8.46nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306462(5-fluoro-3-(1-(2-(5-fluorobenzofuran-3-yl)ethyl)-1...)
Affinity DataKi:  9.25nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306473(5-fluoro-3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  10.1nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306463(3-(1-(2-(5-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306472(6-fluoro-3-(1-(2-(7-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306483(3-(1-(2-(6-chlorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306470(3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306476(5-fluoro-3-(1-(2-(7-methoxybenzofuran-3-yl)propyl)...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306478(3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306486(3-(1-(2-(5-chlorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306487(3-(1-(2-(5-chlorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306475(3-(1-(2-(7-methoxybenzofuran-3-yl)propyl)-1,2,3,6-...)
Affinity DataKi:  29.2nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306480(3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  36.1nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306466(7-ethyl-3-(1-(2-(5-methoxybenzofuran-3-yl)ethyl)-1...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306461(3-(1-(2-(5-fluorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  41.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306464(5-fluoro-3-(1-(2-(5-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306467(3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-1,2,3,6-t...)
Affinity DataKi:  56.3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306479(3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  56.3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306468(5-fluoro-3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  66.3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306482(3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306481(3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  156nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306460(3-(1-(2-(5-fluorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306478(3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  248nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306462(5-fluoro-3-(1-(2-(5-fluorobenzofuran-3-yl)ethyl)-1...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306484(3-(1-(2-(6-chlorobenzofuran-3-yl)ethyl)-1,2,3,6-te...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306469(6-fluoro-3-(1-(2-(6-methoxybenzofuran-3-yl)ethyl)-...)
Affinity DataKi:  303nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308782(4-{3-[4-(3-Isopropyl-7-morpholin-4-yl-3H-[1,2,3]-t...)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50327426(1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308780(1-(4-Hydroxymethylphenyl)-3-[4-(3-isopropyl-7-morp...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308784(1-[4-(3-Isopropyl-7-morpholin-4-yl-3H-[1,2,3]-tria...)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308781(4-(3-(4-(3-ethyl-7-morpholino-3H-[1,2,3]triazolo[4...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378663(CHEMBL1204015)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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