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Found 31 with Last Name = 'sashidhara' and Initial = 'kv'
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
University Of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50295172(4-Hydroxy-5-methoxy-4-[(2S,3R)-2-methyl-3-(3-methy...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
University Of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM17446((3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-m...)
Affinity DataIC50:  1nMAssay Description:Inhibition of methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50248768(1,3-dibenzyl urea | CHEMBL504463)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at TRPV1 in rat DRG neuron assessed as inhibition of calcium uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
University Of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50113436(CHEMBL32838 | fumagillin)
Affinity DataIC50:  30nMAssay Description:Inhibition of methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
University Of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM17847(CHEMBL327579 | pyridine-2-carboxylic acid inhibito...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of methionine aminopeptidase 1More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
University Of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50295174(Bengamide A | CHEMBL256279)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
University Of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50295173(Bengamide O | CHEMBL539894)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
University Of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50295174(Bengamide A | CHEMBL256279)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50216502(4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4-tet...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Central Drug Research Institute (Csir)

Curated by ChEMBL
LigandPNGBDBM34168(LOVASTATIN | MLS000069585 | SMR000058779 | US91151...)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of HMG-CoA reductase using HMG-CoA as substrate by spectrophotometry in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Central Drug Research Institute (Csir)

Curated by ChEMBL
LigandPNGBDBM50353742(CHEMBL486985)
Affinity DataIC50:  3.02E+4nMAssay Description:Inhibition of HMG-CoA reductase using HMG-CoA as substrate by spectrophotometry in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
University Of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50295173(Bengamide O | CHEMBL539894)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
University Of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM17847(CHEMBL327579 | pyridine-2-carboxylic acid inhibito...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405699(CHEMBL4174798)
Affinity DataEC50:  234nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405700(CHEMBL4163051)
Affinity DataEC50:  276nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405701(CHEMBL4167588)
Affinity DataEC50:  1.01E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405701(CHEMBL4167588)
Affinity DataEC50:  1.02E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405700(CHEMBL4163051)
Affinity DataEC50:  275nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405699(CHEMBL4174798)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  1.69E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405698(CHEMBL4159670)
Affinity DataEC50:  454nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405699(CHEMBL4174798)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataEC50:  2.73E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405699(CHEMBL4174798)
Affinity DataEC50:  232nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataEC50:  2.75E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405698(CHEMBL4159670)
Affinity DataEC50:  457nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed