Affinity DataKi: 15nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Binding affinity to adrenergic Alpha-1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to beta-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to adrenergic alpha-1b receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to beta2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.49E+3nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.13E+3nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.42E+3nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 7.47E+4nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.96E+4nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 2.25E+5nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 2.32E+5nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+5nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human Erg expressed in HEK293 cells by whole cell patch clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant AurKA after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1(Homo sapiens)
Neuromed Pharmaceuticals
Curated by ChEMBL
Neuromed Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human Erg expressed in HEK293 cells by whole cell patch clamp analysisMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1(Homo sapiens)
Neuromed Pharmaceuticals
Curated by ChEMBL
Neuromed Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Rattus norvegicus)
University Of Calgary
Curated by ChEMBL
University Of Calgary
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1(Homo sapiens)
Neuromed Pharmaceuticals
Curated by ChEMBL
Neuromed Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1(Homo sapiens)
Neuromed Pharmaceuticals
Curated by ChEMBL
Neuromed Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Rattus norvegicus)
University Of Calgary
Curated by ChEMBL
University Of Calgary
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1(Homo sapiens)
Neuromed Pharmaceuticals
Curated by ChEMBL
Neuromed Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant AurKB after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1(Homo sapiens)
Neuromed Pharmaceuticals
Curated by ChEMBL
Neuromed Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Rattus norvegicus)
University Of Calgary
Curated by ChEMBL
University Of Calgary
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1(Homo sapiens)
Neuromed Pharmaceuticals
Curated by ChEMBL
Neuromed Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Rattus norvegicus)
University Of Calgary
Curated by ChEMBL
University Of Calgary
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Rattus norvegicus)
University Of Calgary
Curated by ChEMBL
University Of Calgary
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1(Rattus norvegicus)
University Of Calgary
Curated by ChEMBL
University Of Calgary
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair