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Found 256 with Last Name = 'schewe' and Initial = 'ke'
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273814(6-Isoquinolin-4-yl-1-methyl-3,4-dihydroquinolin-2(...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273781(6-(5-methoxypyridin-3-yl)-1-methyl-3,4-dihydroquin...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273813(6-Isoquinolin-4-yl-3,4-dihydroquinolin-2(1H)-one |...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272321(3-(Methoxymethyl)-5-(6-methoxynaphthalen-2-yl)pyri...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272366(3-(1-Methoxyethyl)-5-(6-methoxynaphthalen-2-yl)pyr...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272370(4-(6-Methoxy-3-methyl-3,4-dihydronaphthalen-2-yl)i...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272365(1-[5-(6-Methoxynaphthalen-2-yl)-pyridin-3-yl]ethan...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272247(6-(4-Methylpyridin-3-yl)-2-naphthonitrile | CHEMBL...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272368(4-(6-Methoxynaphthalen-2-yl)isoquinoline | CHEMBL5...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272289(CHEMBL500146 | Methyl 5-(6-methoxynaphthalen-2-yl)...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272246(3-(6-Methoxynaphthalen-2-yl)-4-methylpyridine | CH...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272287(3-Methoxy-5-(6-methoxy-3-methyl-3,4-dihydronaphtha...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273700(6-Pyridin-3-yl-3,4-dihydronaphthalene-2-carbonitri...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272291(1-[5-(6-Methoxynaphthalen-2-yl)pyridin-3-yl]ethano...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8891(3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272323(4-(Methoxymethyl)-3-(6-methoxynaphthalen-2-yl)pyri...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273776(1-Methyl-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273780(6-(5-Methoxypyridin-3-yl)-3,4-dihydroquinolin-2(1H...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253499(4-(3-Pyridin-3-yl-naphthalen-2-ylmethyl)benzonitri...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8909(6-(pyridin-3-yl)naphthalene-2-carbonitrile | 6-Pyr...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253574(4-[3-(4-Methoxybenzyl)naphthalen-2-yl]isoquinoline...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272369(4-(6-Methoxy-3-methylnaphthalen-2-yl)isoquinoline ...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273815(6-Pyridin-3-yl-3,4-dihydroquinoline-2(1H)-thione |...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272195(3-(6-Methoxy-3-methyl-3,4-dihydronaphthalen-2-yl)p...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272251(3-Methoxy-5-(6-methoxy-3-methylnaphthalen-2-yl)pyr...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273778(8-Chloro-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253545(3-[3-(4-Trifluoromethoxybenzyl)naphthalen-2-yl]pyr...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272250(3-methoxy-5-(6-methoxynaphthalen-2-yl)pyridine | C...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273816(8-Chloro-6-pyridin-3-yl-3,4-dihydroquinoline-2(1H)...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273704(5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one | CHEMBL...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272245(6-(Pyridin-3-yl)-7,8-dihydronaphthalene-2-carbonit...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272367(3-(6-Methoxynaphthalen-2-yl)-5-phenylpyridine | CH...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253575(4-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]is...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273679(6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalene-2-car...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272288(3-Ethoxy-5-(6-methoxynaphthalen-2-yl)pyridine | CH...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216367(CHEMBL243961 | biphenyl-4-yl-(3-imidazol-1-ylmethy...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8905(3-(6-Methoxy-2-naphthyl)pyridine | 3-(6-methoxynap...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8905(3-(6-Methoxy-2-naphthyl)pyridine | 3-(6-methoxynap...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273814(6-Isoquinolin-4-yl-1-methyl-3,4-dihydroquinolin-2(...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272319(CHEMBL526339 | Methyl [5-(6-methoxynaphthalen-2-yl...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50191600(3-((1H-imidazol-1-yl)methyl)-2-(4-methoxyphenyl)-4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272194(3-(6-Methoxy-3-methylnaphthalen-2-yl)pyridine | CH...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216364((3-((1H-imidazol-1-yl)methyl)phenyl)(phenyl)methan...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253548(3-Methoxy-5-[6-methoxy-3-(4-methoxybenzyl)naphthal...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50253547(3-Methoxy-5-[3-(4-methoxybenzyl)naphthalen-2-yl]py...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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