Affinity DataKi: 0.380nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Competitive inhibition of human Aurora B ATP binding site by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Competitive inhibition of human Aurora C ATP binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Compound was tested for the inhibition of Delta-(24)-sterol reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Competitive inhibition of Aurora C ATP binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Compound was tested for the inhibition of Delta-(24)-sterol reductaseMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity against IL-1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity against IL-1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 393nMAssay Description:Inhibition of human matriptase using Mes-D-Pro-Arg-AMC.2TFA as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 398nMAssay Description:Inhibition of recombinant hexahistidine tagged human MT-SP1 (596 to 855 residues) expressed in Escherichia coli BL21 gold (DE3) cells using Boc-Leu-A...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 459nMAssay Description:Inhibition of recombinant hexahistidine tagged human MT-SP1 (596 to 855 residues) expressed in Escherichia coli BL21 gold (DE3) cells using Boc-Leu-A...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 490nMAssay Description:Competitive inhibition of human Aurora A ATP binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 775nMAssay Description:Inhibition of recombinant hexahistidine tagged human MT-SP1 (596 to 855 residues) expressed in Escherichia coli BL21 gold (DE3) cells using Boc-Leu-A...More data for this Ligand-Target Pair
Ligand Info
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Compound was tested for the inhibition of Delta-(24)-sterol reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.23E+3nMAssay Description:Inhibition of human matriptase using Mes-D-Pro-Arg-AMC.2TFA as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 7.67E+3nMAssay Description:Binding affinity to DENV2 NS2B-NS3 protease by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.84E+4nMAssay Description:Inhibition of recombinant hexahistidine tagged human MT-SP1 (596 to 855 residues) expressed in Escherichia coli BL21 gold (DE3) cells using Boc-Leu-A...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132G](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 2.90nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 3.80nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 4.60nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair