Found 619 with Last Name = 'seal' and Initial = 'jt' 
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Binding affinity against 5-hydroxytryptamine 6 receptor of human caudateMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity against 5-hydroxytryptamine 6 receptor of rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 9nMpH: 5.3Assay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by whole cell patch clamp a...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD3 BD2/BD1 Y73A mutant (1 to 435 residues) (unknown origin) measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD2 domain Y390A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD2 domain Y390A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD2 domain Y390A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 30 mins in presence of fluorescent ligand by TR-FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Binding affinity to 6His-FLAG-Tev-BRDT (1 to 397 residues) BD2 domain Y309A or Y66A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRDT BD2/BD1 Y66A mutant (1 to 397 residues) (unknown origin) measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of 6His-Thr-BRD3 (1 to 435 residues) BD2 domain Y348A or Y73A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Binding affinity to 6His-Thr-BRD3 (1 to 435 residues) BD2 domain Y348A or Y73A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human C-terminal BRD4 bromodomain expressed in Escherichia coli BL21(DE3) after 30 mins by luminescence proximity homogeneous assayMore data for this Ligand-Target Pair
