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TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM196124(US9206232, 125)
Affinity DataIC50: <0.300nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110357(US8613914, 125 | US9206232, 129)
Affinity DataIC50: <0.300nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110396(US8613914, 170 | US9206232, 170)
Affinity DataIC50:  0.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110396(US8613914, 170 | US9206232, 170)
Affinity DataIC50:  0.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110400(US8613914, 174 | US9206232, 174)
Affinity DataIC50:  0.600nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110393(US8613914, 167 | US9206232, 167)
Affinity DataIC50:  0.600nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110400(US8613914, 174 | US9206232, 174)
Affinity DataIC50:  0.600nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110393(US8613914, 167 | US9206232, 167)
Affinity DataIC50:  0.600nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110388(US8613914, 162 | US9206232, 162)
Affinity DataIC50:  0.800nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110388(US8613914, 162 | US9206232, 162)
Affinity DataIC50:  0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM196120(US9206232, 77)
Affinity DataIC50:  0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110280(US8613914, 48 | US9206232, 48)
Affinity DataIC50:  0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110273(US8613914, 41 | US9206232, 41)
Affinity DataIC50:  0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110388(US8613914, 162 | US9206232, 162)
Affinity DataIC50:  0.900nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110309(US8613914, 77)
Affinity DataIC50:  0.900nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110273(US8613914, 41 | US9206232, 41)
Affinity DataIC50:  0.900nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110280(US8613914, 48 | US9206232, 48)
Affinity DataIC50:  0.900nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110277(US8613914, 45 | US9206232, 45)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110383(US8613914, 157 | US9206232, 157)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110294(US8613914, 62 | US9206232, 62)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110397(US8613914, 171 | US9206232, 171)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110397(US8613914, 171 | US9206232, 171)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110264(US8613914, 32 | US9206232, 32)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110294(US8613914, 62 | US9206232, 62)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110383(US8613914, 157 | US9206232, 157)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110264(US8613914, 32 | US9206232, 32)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110277(US8613914, 45 | US9206232, 45)
Affinity DataIC50:  1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110378(US8613914, 152 | US9206232, 152)
Affinity DataIC50:  1.10nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110378(US8613914, 152 | US9206232, 152)
Affinity DataIC50:  1.10nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110295(US8613914, 63 | US9206232, 63)
Affinity DataIC50:  1.20nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110295(US8613914, 63 | US9206232, 63)
Affinity DataIC50:  1.20nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110382(US8613914, 156 | US9206232, 156)
Affinity DataIC50:  1.30nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110382(US8613914, 156 | US9206232, 156)
Affinity DataIC50:  1.30nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110344(US8613914, 112 | US9206232, 112)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110360(US8613914, 128 | US9206232, 128)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110360(US8613914, 128 | US9206232, 128)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110354(US8613914, 122 | US9206232, 122)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110287(US8613914, 55 | US9206232, 55)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110287(US8613914, 55 | US9206232, 55)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110354(US8613914, 122 | US9206232, 122)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110344(US8613914, 112 | US9206232, 112)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM196129(US9206232, 149)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110375(US8613914, 147 | US9206232, 147)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110395(US8613914, 169 | US9206232, 169)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110356(US8613914, 124 | US9206232, 124)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110395(US8613914, 169 | US9206232, 169)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110375(US8613914, 147 | US9206232, 147)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110326(US8613914, 94 | US9206232, 94)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Novartis

US Patent
LigandPNGBDBM110326(US8613914, 94 | US9206232, 94)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Novartis

US Patent
LigandPNGBDBM110356(US8613914, 124 | US9206232, 124)
Affinity DataIC50:  1.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In DepthDetails US Patent
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