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Found 304 with Last Name = 'serafinowska' and Initial = 'ht'
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219087(CHEMBL97637)
Affinity DataKi:  0.501nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219087(CHEMBL97637)
Affinity DataKi:  0.501nMAssay Description:Binding affinity to human cloned 5-HT6 receptor in HeLa cells using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219081(CHEMBL261917)
Affinity DataKi:  0.631nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50130286(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataKi:  0.631nMAssay Description:The compound was tested for the binding affinity towards human cloned 5-hydroxytryptamine 6 receptor in HeLa cells, using [3H]5-LSD as radioligand; n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219081(CHEMBL261917)
Affinity DataKi:  0.631nMAssay Description:Binding affinity to human cloned 5-hydroxytryptamine 6 receptor in HeLa cells using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412434(CHEMBL483365)
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50001824(CHEMBL282971)
Affinity DataKi:  0.794nMAssay Description:The compound was tested for the binding affinity towards human cloned 5-hydroxytryptamine 6 receptor in HeLa cells, using [3H]5-LSD as radioligand; n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50130270(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataKi:  0.794nMAssay Description:The compound was tested for the binding affinity towards human cloned 5-hydroxytryptamine 6 receptor in HeLa cells, using [3H]5-LSD as radioligand; n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219084(CHEMBL97596)
Affinity DataKi:  1nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219089(CHEMBL318018)
Affinity DataKi:  1nMAssay Description:Binding affinity to human cloned 5-HT6 receptor in HeLa cells using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219084(CHEMBL97596)
Affinity DataKi:  1nMAssay Description:Binding affinity to human cloned 5-HT6 receptor in HeLa cells using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219089(CHEMBL318018)
Affinity DataKi:  1nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219083(CHEMBL316081)
Affinity DataKi:  1nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50412939(CHEMBL479463 | GSK-256471)
Affinity DataKi:  1nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219083(CHEMBL316081)
Affinity DataKi:  1nMAssay Description:Binding affinity to human cloned 5-HT6 receptor in HeLa cells using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50412941(CHEMBL521416)
Affinity DataKi:  1.26nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50412940(CHEMBL519770)
Affinity DataKi:  1.26nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219082(CHEMBL95823)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human cloned 5-HT6 receptor in HeLa cells using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219085(CHEMBL97211)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219086(CHEMBL98965)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human cloned 5-HT6 receptor in HeLa cells using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219090(CHEMBL95388)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28583(5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219085(CHEMBL97211)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human cloned 5-HT6 receptor in HeLa cells using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219086(CHEMBL98965)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219082(CHEMBL95823)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28583(5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...)
Affinity DataKi:  1.30nMAssay Description:The compound was tested for the binding affinity towards human cloned 5-hydroxytryptamine 6 receptor in HeLa cells, using [3H]LSD as radioligand; n=3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412114(CHEMBL183460 | SB-649915)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50412942(CHEMBL480249)
Affinity DataKi:  1.58nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219096(CHEMBL99982)
Affinity DataKi:  1.60nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219100(CHEMBL95878)
Affinity DataKi:  1.60nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50001825(CHEMBL97158 | SB-331711)
Affinity DataKi:  2nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50412943(CHEMBL480818)
Affinity DataKi:  2nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50001825(CHEMBL97158 | SB-331711)
Affinity DataKi:  2nMAssay Description:Binding affinity to human cloned 5-HT6 receptor in HeLa cells using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219095(CHEMBL94988)
Affinity DataKi:  2nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219099(CHEMBL98353)
Affinity DataKi:  2nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219127(CHEMBL316643)
Affinity DataKi:  2nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219128(CHEMBL95568)
Affinity DataKi:  2nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219098(CHEMBL97899)
Affinity DataKi:  2.5nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412114(CHEMBL183460 | SB-649915)
Affinity DataKi:  2.51nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412440(CHEMBL485395)
Affinity DataKi:  2.51nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50412944(CHEMBL479652)
Affinity DataKi:  3.16nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219092(CHEMBL329482)
Affinity DataKi:  3.20nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50412945(CHEMBL516441)
Affinity DataKi:  3.98nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412441(CHEMBL490417 | SB-744185)
Affinity DataKi:  3.98nMAssay Description:Inhibition of [3H]5HT reuptake at SERT in rat cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219091(CHEMBL318262)
Affinity DataKi:  4nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219439(CHEMBL29410)
Affinity DataKi:  5nMAssay Description:The compound was tested for the binding affinity towards human cloned 5-hydroxytryptamine 6 receptor in HeLa cells, using [3H]5-LSD as radioligand; n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219097(CHEMBL95511)
Affinity DataKi:  5nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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